Retrospective Study of Extreme Drug Resistant Acinetobacter Baumannii Isolated From Clinical Samples

Abstract

Background:Acinetobacter species specifically A. baumannii is increasingly becoming resistant to most antimicrobial agents recommended for treatment. This study aimed to determine the antimicrobial susceptibility pattern of A.baumannii isolated from patients in Gautam Budha Nagar. retrospective study Material and Methods: This was a based on VITEK 2 (BioMérieux) electronic records capturing identification and antimicrobial susceptibility of Acinetobacter isolates from patient samples analyzed between Jan 2021 and Mar 2023 at GIMS Hospital, Gautam Budha Nagar. A total of 450 Results: A.baumannii were recored. 73.1% of the isolates tested were extreme drug resistant (XDR). Among the 450 isolates, 153 (34%) were from sputum and 176(39%) from the critical care unit. A. baumannii was the most frequently isolated species with high resistant high level of resistance to cephalosporins (91%), ciprofloxacin (96%), and meropenem (76%). It showed susceptibility to colistin only. Conclusion: A. baumannii is resistant to commonly administered antibiotics. There is need for continuous antimicrobial resistance surveillance especially in health care facilities and strengthening of antibiotic stewardship programmes which will contribute to enhancement of infection control policies.