Retrospective study of biopsied head and neck lesions in a cohort of referral Taiwanese patients

Abstract

IntroductionA study of the whole spectrum of biopsied head and neck (HN) diseases in Taiwan has not yet been performed. Therefore, the current study aimed to provide updated information about HN lesions in a cohort of referral Taiwanese patients for histopathological examination.MethodsHN lesions (2000–2011) in patients with records of age, sex, and histological diagnoses were retrieved from the Oral Pathology Department of the institution. These lesions were classified into four main categories: tumor/tumor-like reactive lesions, cystic/pseudocystic lesions, inflammatory/infective lesions, and others/miscellaneous lesions.ResultsA total of 37,210 HN lesions were included in the current study. Most of these lesions were distributed in the group of tumor/tumor-like reactive lesions, followed by the groups of inflammatory/infective lesions, cystic/pseudocystic lesions, and others/miscellaneous lesions. Squamous cell carcinoma was the most common HN lesion, and was also the most frequent malignant lesion among the referral patients.ConclusionIt was worthy of note that squamous cell carcinoma and oral potentially malignant disorders comprised high percentages of all HN lesions for the present cohort of referral patients.

Histopathological patterns of head and neck lesions - a two year retrospective hospital based study

“…11 Our research study showed a preponderance of males in all three histopathological categories which was in accord with the findings of Siddiqui M S et al 15 A wide variety of lesions spanned across the seven topographic sites we analyzed. Lesions arising from the skin and the soft tissues were found to be maximum (29.65%) in present study.…”

“…In a study by Kanu OO et al, more number of benign cases (63.3%) were reported which was compatible with our study. 3 However, least number of benign lesions were noted in the study by Lei F et al 11 The benign lesions were more frequent in the age group of 20 to 50 years while higher percentage of malignant lesions belonged to age group of 51years and above in our research work. These observations were in agreement with the findings of Popat V et al 5 Inflammatory lesions were maximum in the younger age of 20 years and below in our analysis.…”

“…In a study by Lei F et al, most lesions were distributed in a slightly higher age range of 50 to 59 years, followed by 40 to 49 years, and 30 to 39 years, all of which together comprised of 70.0% of all head and neck lesions. 11 In another study conducted by Urooj A et al, the age ranged between 1.5 to 80 years, which varied only slightly from present study. In their study, the most affected age group was <30 years (41.40%) which was lower than what was observed in our study and least number of cases were reported in age group of 61 years and above, which was almost similar to the observation made by us.…”

“…However, Lei F et al, in their research, noted a male to female ratio of 3.4:1, which was much higher than what was observed in our data analysis. 11 This could probably be because of a very large sample size of their study as compared to ours and because of different demographics of our regions.…”

“…Lei F et al, however, reported fibromas as the commonest benign skin and soft tissue lesion followed by hemangiomas while epidermoid cyst was observed to be the most frequent entity among the non-odontogenic cystic lesions. 11 In present study, the malignant lesions predominantly seen in skin and soft tissues was basal cell carcinoma followed by cutaneous squamous cell carcinoma. This was in accord with observation of Hsieh CY et al 16 Oral cavity lesions constituted 20.69% of present study and were found to be more common in males.…”