Retrospective Study of 383 Cases of Fibro-Osseous Lesions of the Jaws

Kato, Camila de Nazaré Alves de Oliveira; Nunes, Laiz Fernandes Mendes; Chalub, Loliza Luiz Figueiredo Houri; Etges, Adriana; Silva, Tarcı́lia Aparecida; Mesquita, Ricardo Alves

doi:10.1016/j.joms.2018.04.037

Cited by 15 publications

(25 citation statements)

References 39 publications

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“…In our region the FOL prevalence was 1.84% (92/5000) within a 3-year period in a sample of the Turkish population. In Spain, it was 0.88% (11/1238) (13) and in Brazil 1.36% (383/27998) (25) , similar to our study. In Thailand, the prevalence was slightly higher which is 2.53% (122/4808) (17) , while another Thai study reports 207 cases within a 38-year period with a prevalence of 1.07% (18) .…”

Section: Discussionsupporting

confidence: 91%

The Prevalence and Analysis of Fibro-osseous Lesions of the Jaws in a Turkish Population Fibro-Osseous Lesions of the Jaws

et al. 2019

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3) osseous dysplasia (OD) (5) . This was a practical classification based on the World Health Organization's (WHO) criteria. OD has different subtypes. There is some evidence that florid osseous dysplasia (FLOD) is a progressive form of focal osseous dysplasia (FOD) . FLOD may be one of its presentations or an early stage of the florid Correspondence to： Aysegul Apaydin Fibro-osseous lesions (FOL) of the jaws are a diverse group which characterized by substitution of normal bone with, various mineralized materials. They refer to different entities which present similar radiological, histopathological features but different biological behavior. We aimed to analyze the features, relative frequencies of various fibro-osseous lesions of jaws in Turkish population. This study included 5000 cases were analyzed in a period 2015-2018. Cone Beam Computed Tomography and panoramic x rays were collected. Patients sex, age, clinical, radiological characteristics were evaluated with histopathological diagnosis. The statistical analysis was carried out using SPSS, student-t and Kruskal-Wallis tests. 92 cases were diagnosed as FOLs of the jaws, which is % 1, 8 of all patients. The most frequent FOL was osseous dysplasia 70.6 % (n=65) , fibrous dysplasia 19.5% (n= 18) and ossifying fibroma 9.7% (n=9) . Within 65 osseous dysplasia, periapical osseous dysplasia was 23% (n=15) , focal osseous dysplasia 43% (n=28) , florid osseous dysplasia 34% (n=22) . It is important to emphasize that the diagnosis of these lesions should be gained with the examination, radiological features and histopathological study. FOLs constitute different conditions and their treatments are based on the complaint of the patient, lesion type, anatomic location and the size of the lesion. Keywords： fibro-osseous lesions, jaws, fibrous dysplasia, ossifying fibroma, osseous dysplasia

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Section: Discussionsupporting

confidence: 91%

The Prevalence and Analysis of Fibro-osseous Lesions of the Jaws in a Turkish Population Fibro-Osseous Lesions of the Jaws

et al. 2019

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“…A recent study by Kato et al demonstrated a female:male ratio of 1.46:1 concerning MFD in a representative sample of patients with FOLs. In this study, 66% of FD cases occurred in the maxilla . Therefore, these tendencies observed in the present study might just reflect the predilections observed for the FD initial diagnosis.…”

Section: Discussionsupporting

confidence: 55%

Malignant transformation of craniomaxillofacial fibro‐osseous lesions: A systematic review

Wagner

Carlos²,

Romañach

et al. 2019

J Oral Pathology Medicine

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The purpose of this study was to perform a systematic review of the literature concerning all documented cases of malignant transformation of craniomaxillofacial fibro‐osseous lesions (FOLs). Three electronic databases were searched. Data were evaluated descriptively. Kaplan‐Meier survival curves were constructed and compared using the log‐rank test. A critical appraisal of included articles was performed through the Joanna Briggs Institute tool. A total of 19 studies including 27 patients were selected for data extraction. Twenty‐six cases were initially diagnosed as fibrous dysplasia and one as ossifying fibroma. The mean age at the time of malignant transformation was 38.11 years, and the average time from initial diagnosis to malignant transformation was 18.2 years. The male:female ratio was 1:1.2, and the maxilla:mandible ratio was 1.5:1. The histological type of the malignant tumor was predominantly osteosarcoma. Follow‐up was available for 21 patients. The 3‐year overall survival rate was 51%. Mandible tumors and diagnoses other than osteosarcoma tended to have poor survival rates, but no significant difference was identified. We concluded that between all FOLs, only fibrous dysplasia seems to have a considerable increased risk of malignant transformation. Thus, a regular and long follow‐up period is advised.

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“…Participants had been evaluated and clinical information had been compiled by various providers with experience in oral diagnosis during this 28-year timeframe. This study is part of a previous investigation conducted by this research group [8], in which 383 cases of FOL of the jaws were analysed. Permission of the Ethics Board of UFMG (No.…”

Section: Patients and Ethical Approvalmentioning

confidence: 99%

“…CODs are not rare and usually affect women in their 40 s and 50 s, who receive the diagnosis at oral and maxillofacial radiology services or during an appointment with a general practitioner [5][6][7][8]. In clinical and pathological studies worldwide, COD has been described as the most common lesion among the FOL of the jaws, with an estimated frequency of 30% to 70% [9,10].…”

Section: Introductionmentioning

confidence: 99%

“…Analyses of a significant number of COD cases are sparse in the literature [2,6,15,47,48]. Furthermore, the existing epidemiological investigations of FOL of the jaws conducted in Asia, Europe, Africa and South America have reached divergent conclusions with respect to the occurrence and clinicopathological profile of CODs [8,9,15,[47][48][49][50][51]. As far as we know, no summary of data on the clinicoradiographic features and appropriate management of infected COD has been conducted.…”

Section: Introductionmentioning

confidence: 99%

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Infected Cemento-Osseous Dysplasia: Analysis of 66 Cases and Literature Review

Kato

Arruda

Mendes

et al. 2019

Head and Neck Pathol

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The aim of this study was to describe a series with 66 cases of infected cemento-osseous dysplasia (COD) and to discuss the demographic distribution, clinicoradiographic features and treatment of this condition. A study looking back on the diagnoses made at a single Brazilian centre within a 28-year timeframe was performed. A literature review with searches across five databases was also conducted to identify reports on osteomyelitis/infected COD. Descriptive and statistical analyses were performed. The case series study showed a female/male ratio of 21:1. Affected individuals' mean age was 57.4 years. Mandible was the most affected site (95.5%) and florid subtype was the most frequent infected COD (62.1%). Tooth extraction was the main factor associated with the development of infection associated within a COD lesion. The literature review retrieved 30 studies reporting 46 cases of this condition. Asian women in their 40 s and 50 s were more affected. Surgery for removal/curettage of necrotic bone was acknowledged as an appropriate approach to the treatment of this infection. The clinicodemographic data of the study were similar to data collected across the literature. Clinicians, maxillofacial surgeons and oral rehabilitation providers should be alert to the diagnosis of COD, since infection is a frequent complication whose management is challenging.

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Retrospective Study of 383 Cases of Fibro-Osseous Lesions of the Jaws

Cited by 15 publications

References 39 publications

The Prevalence and Analysis of Fibro-osseous Lesions of the Jaws in a Turkish Population Fibro-Osseous Lesions of the Jaws

The Prevalence and Analysis of Fibro-osseous Lesions of the Jaws in a Turkish Population Fibro-Osseous Lesions of the Jaws

Malignant transformation of craniomaxillofacial fibro‐osseous lesions: A systematic review

Infected Cemento-Osseous Dysplasia: Analysis of 66 Cases and Literature Review

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