Retrospective quantitative cartilage and semi-quantitative morphological evaluation at 6 years after ACL reconstruction

Snoj, Žiga; Zupanc, Oskar; Salapura, Vladka

doi:10.1007/s00402-016-2463-3

Cited by 9 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Due to the small number of participants with arthroscopically detected surface defects in the study regions, there was insufficient power to definitively relate higher T2 value to more severe arthroscopic status. While broadly consistent with those of Snoj et al 11 in which T2 elevations in anterofemoral cartilage at 6 years follow-up were associated with meniscal insufficiency detected at arthroscopy, our subanalyses of T2 changes with respect to meniscal tear and repair status and age should be also interpreted with caution because of the small sample sizes. Although no power analyses were performed a priori, all available data were utilized.…”

Section: Discussionsupporting

confidence: 90%

See 1 more Smart Citation

Cartilage Matrix Degeneration Occurs within the First Year after ACLR and Is Associated with Impaired Clinical Outcome

Deadwiler

Dragoo

et al. 2021

CARTILAGE

View full text Add to dashboard Cite

Objective Anterior cruciate ligament reconstruction (ACLR) has not been shown to decrease the risk for development of post-traumatic osteoarthritis. Magnetic resonance imaging (MRI) T2 mapping can be used to assess cartilage compositional changes. This study tests whether (1) worse cartilage arthroscopic status at ACLR is reflected by higher cartilage T2 values in matched study regions 6 weeks and 1 year after ACLR, and (2) increasing cartilage T2 values between 6 weeks and 1 year after ACLR are associated with worsening patient-reported outcomes. Design Twenty-two participants with ACLR and 26 controls underwent 3T MRI. T2 values in medial and lateral femoral and tibial cartilage were measured at 6 weeks and 1 year after ACLR and compared with arthroscopic grades, Knee injury and Osteoarthritis Outcome Scores (KOOS), and control T2 values. Results Most (59%-86%) cartilage study regions examined by arthroscopy demonstrated intact articular surfaces. Average T2 value increased in 3 of 4 study regions between 6 weeks and 1 year after ACLR ( P = .001-.011). T2 value increased ( P < .013) even for participants whose cartilage had intact articular surfaces at ACLR. Participants with ACLR who showed greater increases in cartilage T2 values had less improvement to KOOS Quality of Life ( P = .009, ρ = −0.62). Discussion Cartilage status assessed arthroscopically at ACLR and by MRI T2 maps 6 weeks later was healthier than cartilage status assessed by MRI T2 maps at 1-year follow-up. Progressive T2 elevations were observed over the first year after ACLR even in patients with arthroscopically intact cartilage at the time of surgery and were associated with reduced improvement in knee quality of life suggesting preosteoarthritis.

show abstract

Section: Discussionsupporting

confidence: 90%

“…Patients with ACL reconstruction are among those at high risk of developing OA, especially those with concomitant meniscus injury. 2,3,10 In fact, at a mid-term follow-up of 40 patients at 6 years after ACLR, Snoj et al 11 detected T2 elevations in tibiofemoral cartilage related to meniscal insufficiency.…”

Section: Introductionmentioning

confidence: 99%

Cartilage Matrix Degeneration Occurs within the First Year after ACLR and Is Associated with Impaired Clinical Outcome

Deadwiler

Dragoo

et al. 2021

CARTILAGE

View full text Add to dashboard Cite

show abstract

“…Patients were instructed to avoid sport activities one day prior to the MRI examination and were scanned in a supine position after resting at least half an hour in order to minimize the changes of different loading conditions before the MRI examination. The same imaging protocol was used as described in our previous paper and included proton density (PD) turbo spin echo (TSE) fat saturation (FS) [15].…”

Section: Imaging Protocolsmentioning

confidence: 99%

“…Knee joint cartilage was manually segmented in accordance with previously reported papers and five compartments were defined: lateral femoral, medial femoral, lateral tibial, medial tibial and patella [15,17,18]. These were subdivided into subcompartments with regard to the menisci in a fashion of the regional subdivision used in WORMS [15,16].…”

Section: Semi-quantitative Mri Assessmentmentioning

confidence: 99%

See 1 more Smart Citation

A descriptive study of potential effect of anterior tibial translation, femoral tunnel and anterior cruciate ligament graft inclination on clinical outcome and degenerative changes

Snoj

Zupanc

Stražar

et al. 2017

International Orthopaedics (SICOT)

Self Cite

View full text Add to dashboard Cite

Introduction There is no evidence that anatomically correct anterior cruciate ligament reconstruction (ACLR) offers lower rate of degenerative changes development or that it would lead to a better outcome. The significance and understanding of the abnormal anterior tibial translation (ATT) in ACLR patients is yet to be established. Methods Sixty subjects (40 patients at 5.9 years after ACLR, 20 healthy controls) underwent 3 T MRI. Quantitative cartilage T2 mapping and morphological whole organ magnetic resonance imaging score (WORMS) evaluation was performed. Self-reported questionnaires were used for subjective clinical evaluation. Correlations were calculated with the following MRI measurements; femoral tunnel inclination, ACL graft inclination, lateral and medial compartment ATT. Results In the ACLR group positive correlation was found between the patellar cartilage T2 values and sagittal ACL graft inclination. In the ACLR group lateral compartment ATT showed negative correlation with ACL graft inclination and subjective clinical evaluation, and positive correlation with morphological degenerative changes. Femoral tunnel showed positive correlation with ACL graft inclination in the same plane. Conclusions Increased ATT offers worse clinical outcome and increased rate of degenerative changes. Furthermore, ATT is affected by the ACL inclination. Inclination of the drilling tunnel affects ACL graft inclination; thereby independent drilling techniques provide superior results of anatomical ACL graft positioning.

show abstract

Patellofemoral joint cartilage lesions frequently develop shortly after anterior cruciate ligament reconstruction using hamstring tendon autograft: A systematic review

Han,

Jung,

Chung

et al. 2024

Knee surg. sports traumatol. arthrosc.

View full text Add to dashboard Cite

PurposeThis study aimed to investigate the development of patellofemoral joint (PFJ) cartilage lesions following anterior cruciate ligament reconstruction (ACLR) using hamstring tendon (HT) autograft through a systematic review.MethodsA comprehensive search was conducted in PubMed, Embase, Cochrane Library and Google Scholar databases to find articles published from database inception until 15 November 2023. The search terms were [(‘Anterior Cruciate Ligament’ [mesh] OR ‘anterior cruciate ligament’ OR ‘ACL’) AND ‘reconstruction’ AND ‘cartilage’ AND (‘second look arthroscopy’ OR ‘second‐look arthroscopy’ OR ‘MRI’ OR ‘magnetic resonance imaging’)]. Inclusion criteria were studies that reported on the occurrence of PFJ cartilage lesions following ACLR using HT autograft, as determined by second‐look arthroscopy or follow‐up magnetic resonance imaging (MRI).ResultsFifteen studies (1084 patients) met the inclusion criteria, with follow‐up periods ranging from 1 to 5 years. In the results of second‐look arthroscopy, cartilage grade deterioration was observed, ranging from MDs of 0.1 to 2.0 in the patella and from 0 to 1.0 in the trochlea. Follow‐up MRI results reported the incidence of PFJ cartilage degeneration with rates ranging from 20% to 44%. Patient‐reported outcome measures often showed no significant association with PFJ cartilage lesions. The studies included in this review reported various risk factors for cartilage lesion development.ConclusionCartilage lesions in the PFJ, detected using second‐look arthroscopy or follow‐up MRI, frequently develop shortly after ACLR using HT autograft. At this stage, patients might not show specific symptoms; however, those with risk factors require careful observation and evaluation by clinicians during follow‐up.Level of EvidenceLevel IV.

show abstract

Retrospective quantitative cartilage and semi-quantitative morphological evaluation at 6 years after ACL reconstruction

Cited by 9 publications

References 21 publications

Cartilage Matrix Degeneration Occurs within the First Year after ACLR and Is Associated with Impaired Clinical Outcome

Cartilage Matrix Degeneration Occurs within the First Year after ACLR and Is Associated with Impaired Clinical Outcome

A descriptive study of potential effect of anterior tibial translation, femoral tunnel and anterior cruciate ligament graft inclination on clinical outcome and degenerative changes

Patellofemoral joint cartilage lesions frequently develop shortly after anterior cruciate ligament reconstruction using hamstring tendon autograft: A systematic review

Contact Info

Product

Resources

About