Retrospective, matched case-control study comparing the oncologic outcomes between laparoscopic surgery and open surgery in patients with right-sided colon cancer

Nakamura, Takatoshi; Onozato, Wataru; Mitomi, Hiroyuki; Naito, Masanori; Sato, Takeo; Ozawa, Heita; Hatate, Kazuhiko; Ihara, Atsushi; Watanabe, Masahiko

doi:10.1007/s00595-009-4011-z

Cited by 41 publications

(31 citation statements)

References 13 publications

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“…Studies have shown that laparoscopic surgery may reduce the incidence of intestinal obstruction. A study comparing the outcomes between laparoscopic and open surgery for patients with right-sided colon cancer showed less postoperative intestinal obstruction with laparoscopic surgery [19].…”

Section: Discussionmentioning

confidence: 99%

Long-term outcome and survival with laparoscopy-assisted pylorus-preserving gastrectomy for early gastric cancer

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Long-term outcome and survival with laparoscopy-assisted pylorus-preserving gastrectomy for early gastric cancer

et al. 2010

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“…Data showed only a 58% four-year survival rate for patients on the waitlist, compared to a four-year survival rate of 90% after SPK [17]. To put this in perspective, the survival time on the waiting list is worse than for patients with stage 3 colon cancer [18]. Therefore, all patients with type 1 diabetes and impaired kidney function should be transplanted as soon as possible.…”

Section: Discussionmentioning

confidence: 99%

Extended pancreas donor program – the EXPAND study rationale and study protocol

et al. 2013

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BackgroundSimultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenile) diabetes mellitus with or without impaired renal function. Unfortunately, transplant waiting lists for this indication are increasing because the current organ acceptability criteria are restrictive; morbidity and mortality significantly increase with time on the waitlist. Currently, only pancreas organs from donors younger than 50 years of age and with a body mass index (BMI) less than 30 are allocated for transplantation in the Eurotransplant (ET) area. To address this issue we designed a study to increase the available donor pool for these patients.Methods/DesignThis study is a prospective, multicenter (20 German centers), single blinded, non-randomized, two armed trial comparing outcome after SPK, PTA or PAK between organs with the currently allowed donor criteria versus selected organs from donors with extended criteria. Extended donor criteria are defined as organs procured from donors with a BMI of 30 to 34 or a donor age between 50 and 60 years. Immunosuppression is generally standardized using induction therapy with Myfortic, tacrolimus and low dose steroids. In principle, all patients on the waitlist for primary SPK, PTA or PAK are eligible for the clinical trial when they consent to possibly receiving an extended donor criteria organ. Patients receiving an organ meeting the current standard criteria for pancreas allocation (control arm) are compared to those receiving extended criteria organ (study arm); patients are blinded for a follow-up period of one year. The combined primary endpoint is survival of the pancreas allograft and pancreas allograft function after three months, as an early relevant outcome parameter for pancreas transplantation.DiscussionThe EXPAND Study has been initiated to investigate the hypothesis that locally allocated extended criteria organs can be transplanted with similar results compared to the currently allowed standard ET organ allocation. If our study shows a favorable comparison to standard organ allocation criteria, the morbidity and mortality for patients waiting for transplantation could be reduced in the future.Trial registrationTrial registered at: NCT01384006

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“…With the recent publication of several landmark trials confirming the safety and effectiveness of a laparoscopic approach for both benign and malignant colorectal pathology [5][6][7], it is expected that the demand for a laparoscopic colorectal surgery will increase. However, most operations are performed using a laparoscopically assisted technique, whereby extracorporeal bowel division and anastomosis are carried out after laparoscopic mobilization of the bowel [8,9].…”

Section: Introductionmentioning

confidence: 99%

Totally laparoscopic colectomy with intracorporeal anastomosis achieved using a laparoscopic linear stapler: experience of a single institute

et al. 2011

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Intracorporeal functional end-to-end anastomosis using a linear stapler can be performed safely and easily for the resection of any part of the colon. We consider it an effective modality for totally laparoscopic colon resection. Favorable results have been achieved by this method, particularly for small tumors, since natural-orifice transluminal endoscopic surgery remains a challenging method to perform.

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Retrospective, matched case-control study comparing the oncologic outcomes between laparoscopic surgery and open surgery in patients with right-sided colon cancer

Abstract: An LRHC for right-sided colon cancer has the advantage over an ORHC of better short-term outcomes, and both groups have similar long-term oncologic outcomes. An LRHC is thus an acceptable alternative to an ORHC for the treatment of this type cancer.

Cited by 41 publications

References 13 publications

Long-term outcome and survival with laparoscopy-assisted pylorus-preserving gastrectomy for early gastric cancer

Long-term outcome and survival with laparoscopy-assisted pylorus-preserving gastrectomy for early gastric cancer

Extended pancreas donor program – the EXPAND study rationale and study protocol

Totally laparoscopic colectomy with intracorporeal anastomosis achieved using a laparoscopic linear stapler: experience of a single institute

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