Retrospective evaluation of the effect of high flow oxygen therapy delivered by nasal cannula on PaO₂ in dogs with moderate‐to‐severe hypoxemia

Abstract

These data suggest HFOT is a viable clinical intervention for dogs with moderate-to-severe hypoxemia assessed to be failing TOT. Further studies are needed to determine if HFOT can be used as an alternative to mechanical ventilation in resource limited settings and to characterize the complications associated with this therapy.

Prospective pilot study for evaluation of high‐flow oxygen therapy in dyspnoeic dogs: the HOT‐DOG study

“…() in healthy dogs and Keir et al . () in hypoxaemic dogs also showed this PaO 2 improvement after HOT. With such an increase in PaO 2 during a short period of time, HOT raises concern for oxygen toxicity if continued for a long period.…”

“…In one veterinary study in hypoxaemic dogs, HOT intolerance requiring sedation was noticed in one of six dogs (Keir et al . ). Jagodich et al .…”

“…No clinically relevant complications related to the oxygen therapy technique were noted during our study, which therefore supports previously published studies of HOT safety in dogs (Keir et al . , Daly et al . , Jagodich et al .…”

“…), and a preliminary retrospective study described its successful use in six hypoxaemic dogs (Keir et al . ). No prospective study reporting the use of HOT in dyspnoeic dogs has been conducted.…”

“…HOT has recently been shown to be a safe and effective method for oxygen delivery in sedated and awake healthy dogs (Daly et al 2017, Jagodich et al 2019, and a preliminary retrospective study described its successful use in six hypoxaemic dogs (Keir et al 2016). No prospective study reporting the use of HOT in dyspnoeic dogs has been conducted.…”