Abstract:In the 1970s it was statistically proved that exposure to radon daughter products caused lung cancer in miners. High concentrations of radon daughters have since been found in houses. Any epidemiological radon study begun today is hampered because relevant exposure data are difficult to obtain owing to the long latency period between exposure and tumour manifestation. Here I present a method for measuring cumulative radon daughter levels, which takes advantage of the fact that the first long-lived radon daught… Show more
“…The 210 Pb has been accumulated over many years on the surface of solid media (mostly glass), known as surface traps (ST) [5][6][7][8], or in the bulk of porous media (mostly furniture filling sponges), known as volume traps (VT) [9]. Activity of 210 Po can be related to the long-term average indoor radon concentration.…”
Section: Retrospective Assessment Of Radon Exposure (Rare) Techniquesmentioning
Abstract. The paper deals with a specific aspect of a general survey, that is being carried out during last ten years in several regions of Serbia (former Yugoslavia, former Serbia and Montenegro) to assess population exposure to natural radioactivity based on geochemical and integrative pattern research approach. The originality regarding this work is related to the facts such as follows: the first identification and assessment of high areas of natural radiation in Serbia which provides insight into its regional characteristics, the interpretation of the results in terms of geological aspects, building types and human habits, the first introduction and field applicability of both (surface and volume trap) retro techniques in Serbia and assessment of doses and risks to the population in investigated high natural radiation rural communities.
“…The 210 Pb has been accumulated over many years on the surface of solid media (mostly glass), known as surface traps (ST) [5][6][7][8], or in the bulk of porous media (mostly furniture filling sponges), known as volume traps (VT) [9]. Activity of 210 Po can be related to the long-term average indoor radon concentration.…”
Section: Retrospective Assessment Of Radon Exposure (Rare) Techniquesmentioning
Abstract. The paper deals with a specific aspect of a general survey, that is being carried out during last ten years in several regions of Serbia (former Yugoslavia, former Serbia and Montenegro) to assess population exposure to natural radioactivity based on geochemical and integrative pattern research approach. The originality regarding this work is related to the facts such as follows: the first identification and assessment of high areas of natural radiation in Serbia which provides insight into its regional characteristics, the interpretation of the results in terms of geological aspects, building types and human habits, the first introduction and field applicability of both (surface and volume trap) retro techniques in Serbia and assessment of doses and risks to the population in investigated high natural radiation rural communities.
“…Long-lived progeny embedded in the surface of glass over time emit alpha particles, which can be counted as an index of the concentration of radon to which the glass has been exposed (24,25). This approach has now been incorporated into several of the case-control studies (26,24-).…”
Section: Radon and Lung Cancer: An Overviewmentioning
Radon is a well-established human carcinogen for which extensive data are available, extending into the range of exposures experienced by the general population. Mounting epidemiologic evidence on radon and lung cancer risk, now available from more than 20 different studies of underground miners and complementary laboratory findings, indicates that risks are linear in exposure without threshold. Radon is also a ubiquitous indoor air pollutant in homes, and risk projections imply that radon is the second leading cause of lung cancer after smoking. Recommended control strategies in the United States and other countries, which include testing of most homes and mitigation of those exceeding guideline levels, have been controversial. Further research is needed, drawing on molecular and cellular approaches and continuing the follow-up of the underground miner cohorts, and scientists should work toward constructing mechanistically based models that combine epidemiologic and experimental data to yield risk estimates with enhanced certainty. Key words: lung cancer, radon, radon progeny, risk assessment. -Environ Health Perspect 1 08(suppl 4):635-641 (2000). http.//ehpnetl.niehs.nih.gov/docs/2000/suppl-4/635-64 lsamet/abstracthtml
“…A recently developed glass -based methodology may provide improved estimates for the historical average radon concentrations to which subjects have been exposed indoors (Samuelsson, 1988;Mahaffey et al, 1993 ). This methodology involves assessment of the past average concentrations through measurements of the surface activity on a glass object that has been in a subject's dwellings through the whole or the major part of the exposure period of interest.…”
Section: Introductionmentioning
confidence: 99%
“…Glass objects can be found in the dwellings currently occupied by the subjects or by their next of kin if the subjects are not alive. The surface activity of hard materials like glass is related to the average radon concentrations during several decades due to the long half -life of 210 Pb ( 22.26 years ), a radon progeny found implanted within their surface as a result of the kinetic energy transferred by alpha decay to the radon progeny atoms plating out on surfaces (Lively and Ney, 1987;Samuelsson, 1988 ). An epidemiologic study recently completed in Missouri showed significantly increased risks when radon was measured with surface monitors but not when air measurements were used to assess residential radon exposure, suggesting that the glass -based methodology allowed more accurate estimation of exposure and of the related lung cancer risk (Alavanja et al, 1999).…”
Lung cancer risk estimation in relation to residential radon exposure remains uncertain, partly as a result of imprecision in air -based retrospective radonexposure assessment in epidemiological studies. A recently developed methodology provides estimates for past radon concentrations and involves measurement of the surface activity of a glass object that has been in a subject's dwellings through the period for exposure assessment. Such glass measurements were performed for 110 lung cancer subjects, diagnosed 1985 to 1995, and for 231 control subjects, recruited in a case -control study of residential radon and lung cancer among never -smokers in Sweden. The relative risks ( with 95% confidence intervals ) of lung cancer in relation to categories of surface -based average domestic radon concentration during three decades, delimited by cutpoints at 50, 80, and 140 Bq m À 3 , were 1.60 ( 0.8 to 3.4 ), 1.96 ( 0.9 to 4.2 ), and 2.20 ( 0.9 to 5.6 ), respectively, with average radon concentrations below 50 Bq m À 3 used as reference category, and with adjustment for other risk factors. These relative risks, and the excess relative risk ( ERR ) of 75% ( À 4% to 430% ) per 100 Bq m À 3 obtained when using a continuous variable for surface -based average radon concentration estimates, were about twice the size of the corresponding relative risks obtained among these subjects when using air -based average radon concentration estimates. This suggests that surface -based estimates may provide a more relevant exposure proxy than air -based estimates for relating past radon exposure to lung cancer risk.
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