Retrospective cohort study of prognostic factors in patients with oral cavity and oropharyngeal squamous cell carcinoma

Carrillo, José F.; Carrillo, Liliana C.; Cano, A.; Ramírez-Ortega, Margarita; Chanona, Jorge G; Avilés, Alejandro; Herrera‐Goepfert, Roberto; Corona-Rivera, Jaime; Ochoa‐Carrillo, Francisco Javier; Oñate‐Ocaña, Luis F.

doi:10.1002/hed.23914

Cited by 28 publications

(19 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Data in this study revealed that mode of invasion is an independent prognostic factor of OS in agreement with the previous studies (1,12,(16)(17)(18), but no relation between mode of invasion and CD57, CD16, and TGF-b expression was seen.…”

Section: Discussionsupporting

confidence: 92%

Prognostic implication of CD57, CD16, and TGF‐β expression in oral squamous cell carcinoma

Taghavi

Bagheri

Akbarzadeh

2015

J Oral Pathology Medicine

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

Prognostic implication of CD57, CD16, and TGF‐β expression in oral squamous cell carcinoma

Taghavi

Bagheri

Akbarzadeh

2015

J Oral Pathology Medicine

View full text Add to dashboard Cite

show abstract

“…It is urgent to identify useful biomarkers to predict occult cervical LNM for patients with cT1‐2N0 OSCC. Several pathological markers are evaluated by many research groups, including lymphocytic infiltration, perineural invasion, vascular invasion, tumor thickness, DOI, and TB . Recently, the eighth edition TNM staging system includes DOI in the definition of T categories for oral cavity cancers .…”

Section: Discussionmentioning

confidence: 99%

Impact of tumor budding in head and neck squamous cell carcinoma: A meta‐analysis

et al. 2018

View full text Add to dashboard Cite

Tumor budding (TB) has been suggested as an adverse prognostic factor in head and neck squamous cell carcinoma (HNSCC). This meta‐analysis evaluated the prognostic role of TB in HNSCC. We systematically reviewed the literatures of electronic databases and performed a meta‐analysis to address the impact of TB on prognosis in HNSCC. Published data were extracted and organized. Then, pooled odds ratios for lymph node metastasis (LNM) and hazard ratios for survival were calculated by using the Mantel‐Haenszel fixed effect model. The results showed that high TB was significantly associated with LNM and worse survival in patients with HNSCC. Moreover, high TB was also correlated with poor prognosis in patients with cT1‐2N0 oral squamous cell carcinoma. TB is a promising prognostic factor associated with LNM and worse survival, which should be included in the routine pathological examination of HNSCC.

show abstract

“…Perineural invasion (PNI), the histologic finding of nerve invasion by tumor cells, is generally accepted as a poor prognostic factor in head and neck squamous cell carcinoma (HNSCC) and has been associated with increased locoregional recurrence and decreased survival . PNI has also been shown to predict concurrent cervical lymph node metastasis, an important negative prognostic factor in early oral cavity cancer .…”

Section: Introductionmentioning

confidence: 99%

Adjuvant radiotherapy for early head and neck squamous cell carcinoma with perineural invasion: A systematic review

2015

View full text Add to dashboard Cite

Perineural invasion (PNI) is widely regarded as a negative prognostic factor in head and neck squamous cell carcinoma (HNSCC). Treatment guidelines recommend adjuvant radiotherapy (RT) for patients with adverse pathologic features, including PNI. The purpose of this study was to systematically review the literature to determine if patients with PNI as their only indication for adjuvant therapy benefit from adjuvant RT. In total, 339 abstracts were reviewed for relevance leaving 85 articles, which were evaluated in detail. Thirteen retrospective studies addressed the role of adjuvant RT for patients with PNI. Evidence is lacking to recommend adjuvant RT for all patients with HNSCC with PNI. However, the literature suggests that large nerve or multifocal PNI may predict worse outcome and may be a more appropriate indication for adjuvant therapy. We advocate that patients decide whether to undergo adjuvant therapy after a discussion of the limitations of current evidence. © 2015 Wiley Periodicals, Inc. Head Neck 38: E2350-E2357, 2016.

show abstract

Retrospective cohort study of prognostic factors in patients with oral cavity and oropharyngeal squamous cell carcinoma

Abstract: Surgical margins, perineural and perivascular invasion, lymphocytic infiltration, and infiltrative patterns of tumor invasion are significant prognostic factors in oral cavity and oropharyngeal SCC.

Cited by 28 publications

References 26 publications

Prognostic implication of CD57, CD16, and TGF‐β expression in oral squamous cell carcinoma

Prognostic implication of CD57, CD16, and TGF‐β expression in oral squamous cell carcinoma

Impact of tumor budding in head and neck squamous cell carcinoma: A meta‐analysis

Adjuvant radiotherapy for early head and neck squamous cell carcinoma with perineural invasion: A systematic review

Contact Info

Product

Resources

About