Retrospective cohort study of gastrointestinal stasis in pet rabbits

Huynh, Minh; Vilmouth, S.; Gonzalez, M. S.; Carrasco, Daniel Calvo; Girolamo, Nicola Di; Forbes, Neil

doi:10.1136/vr.102460

Cited by 24 publications

(13 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The presence of ileus alone, therefore, does not necessarily signify a primary gastrointestinal or even abdominal disease. One previous study reported a prevalence of 25.1 per cent for ileus, with young adult rabbits, dwarf and lop breeds potentially being at increased risk 48 . The study was however performed at an exotics referral practice, so it may not necessarily reflect the whole UK pet rabbit population.…”

Section: Discussionmentioning

confidence: 99%

Morbidity and mortality of domestic rabbits (Oryctolagus cuniculus) under primary veterinary care in England

et al. 2020

View full text Add to dashboard Cite

BackgroundThe domestic rabbit is a common pet species, but limited research exists on the health of pet rabbits. This study aimed to characterise common disorders of pet rabbits and reasons for mortality as recorded by veterinary practices in England.MethodsThis cross-sectional study covered anonymised clinical records of 6349 rabbits attending 107 primary veterinary care clinics.ResultsThe median age was 3.2 years (interquartile range (IQR) 1.6–5.1), and the median adult bodyweight was 2.1 kg (IQR 1.7–2.6). The most common breed types were domestic (n=2022, 31.9 per cent), lop (1675, 26.4 per cent) and Netherland dwarf (672, 10.6 per cent). For those rabbits that died during the study period, the median age at death was 4.3 years (IQR 2.1–7.0). The most common causes of death were recorded as myiasis (prevalence 10.9 per cent, 95 per cent confidence interval (CI): 7.4 to 15.2), anorexia (4.9 per cent, 95 per cent CI: 4.0 to 10.4), recumbency/collapse (4.9 per cent, 95 per cent CI: 4.0 to 10.4) and ileus (4.3 per cent, 95 per cent CI: 3.5 to 9.5). The most prevalent specific disorders recorded were overgrown claw/nails (16.0 per cent, 95 per cent CI: 14.5 to 17.5), overgrown molar(s) (7.6 per cent, 95 per cent CI: 6.6 to 8.7), perineal soiling (4.5 per cent, 95 per cent CI: 3.7 to 5.4), overgrown incisor(s) (4.3 per cent, 95 per cent CI: 3.5 to 5.2) and ileus (4.2 per cent, 95 per cent CI: 3.4 to 5.0).ConclusionsThis study augments the limited evidence base on rabbit health and can assist veterinarians to better advise owners on optimal animal husbandry priorities.

show abstract

Section: Discussionmentioning

confidence: 99%

Morbidity and mortality of domestic rabbits (Oryctolagus cuniculus) under primary veterinary care in England

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The three animals did not gain weight in the week before termination. These deaths were attributed to gastrointestinal stasis, occasionally seen in laboratory rabbits (DeCubellis and Graham, 2013;Huynh et al, 2014). Given that this same pathology was observed in three different groups, including the control group, with no temporal relationship to the days of treatment, the deaths were considered not treatment-related.…”

Section: Generalmentioning

confidence: 97%

Local tolerance and systemic toxicity of single and repeated intramuscular administrations of two different formulations of the RTS,S malaria candidate vaccine in rabbits

Segal

Morelle

Blee

et al. 2015

Regulatory Toxicology and Pharmacology

View full text Add to dashboard Cite

“…The diagnostic and therapeutic approach to the acute rabbit abdomen should be the same as other emergency cases in rabbits ( 27 , 28 ). GI stasis is one of the most common disorders of pet rabbits and is characterised by normal behaviour to apathy, abdominal discomfort, and gradual decline in appetite and production of small, dry faecal pellets ( 29 , 30 ). In contrast, animals with gastric dilation (gastric bloat) suddenly become depressed and anorexic ( 31 ) and, with the onset of hypovolemic shock, body temperature declines.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Spontaneous Appendicitis With Suspected Involvement of Klebsiella variicola in Two Pet Rabbits

Jekl

Piskovska²,

Drnkova³

et al. 2021

Front. Vet. Sci.

View full text Add to dashboard Cite

Although laboratory rabbits are commonly used as models of appendicitis in man, spontaneous appendicitis was only described ante-mortem in one pet rabbit with an acute abdomen. The aim of this article is to describe two spontaneous cases of appendicitis in pet rabbits, to describe therapeutic appendectomy, and to discuss the microbial flora of the inflamed appendix. A 5-month-old intact female and a 16-month-old, neutered male were presented to the veterinary clinic with restlessness, anorexia, and reduced faecal output. The main clinical findings were restlessness, severe discomfort on abdominal palpation, a mid-abdominal palpable tubulous mass and an elevated rectal temperature. Blood analyses showed lymphocytosis, monocytosis, and hyperglycaemia. Radiography was inconclusive. Abdominal ultrasound revealed a presence of a tubular structure with wall thicknesses of 4.2 and 3.7 mm in the two rabbits, respectively. The tubular structure had a rounded, closed end, and a multilayered wall, suggestive of appendicitis. Due to metabolic acidosis and poor prognosis, the first rabbit was euthanized. In the 16-month-old rabbit, appendectomy was performed. Recovery was uneventful, and 4 h after surgery, the rabbit started to become normally active. Postoperative care consisted of fluid therapy, multimodal analgesia, supportive care and prokinetics. Follow-up examinations at 10 days, 1 month, and at 11 months after the surgery did not show any abnormal clinical or laboratory findings. Histopathological examination of appendices from both rabbits showed gangrenous appendicitis. Aerobic cultivation showed the presence of pure culture of Klebsiella variicola sensitive to enrofloxacin, marbofloxacin, tetracycline, cefuroxime, trimethoprim sulphonamide, neomycin, and gentamicin. Restlessness associated with anorexia, abdominal pain, palpable abdominal mass, hyperglycaemia, lymphocytosis, and elevated rectal temperature may be indicative of inflammation within the gastrointestinal tract. Abdominal ultrasound is recommended in rabbits with showing these clinical signs because radiography can be inconclusive. Appendicitis is a life-threatening condition, which should be included into the list of differential diagnoses; for the rabbit, an acute abdomen and gastrointestinal stasis syndrome and must be treated immediately. K. variicola may be associated with appendicitis in rabbits as a causative agent or in association with appendix intraluminal dysmicrobia.

show abstract

Retrospective cohort study of gastrointestinal stasis in pet rabbits

Cited by 24 publications

References 9 publications

Morbidity and mortality of domestic rabbits (Oryctolagus cuniculus) under primary veterinary care in England

Morbidity and mortality of domestic rabbits (Oryctolagus cuniculus) under primary veterinary care in England

Local tolerance and systemic toxicity of single and repeated intramuscular administrations of two different formulations of the RTS,S malaria candidate vaccine in rabbits

Case Report: Spontaneous Appendicitis With Suspected Involvement of Klebsiella variicola in Two Pet Rabbits

Contact Info

Product

Resources

About