Retrospective and prospective validation of Model for End-stage Liver Disease (MELD) score in predicting mortality in patients of alcoholic liver disease

Child–Pugh Versus MELD Score for the Assessment of Prognosis in Liver Cirrhosis

“…The characteristics of the 119 papers were shown in Table 1 . The countries included Austria (n = 1), 11 Belgium (n = 2), 38 , 96 China (n = 26), 20 , 21 , 27 , 30 , 31 , 53 – 55 , 59 , 60 , 74 , 84 , 102 , 109 , 112 , 113 , 117 , 119 – 121 , 123 – 128 Cuba (n = 1), 47 Czech Republic (n = 1), 44 Egypt (n = 1), 51 France (n = 6), 25 , 37 , 41 , 71 , 77 , 114 Germany (n = 7), 12 , 48 – 50 , 92 , 105 , 111 Greece (n = 1), 82 Hungary (n = 1), 61 India (n = 10), 19 , 29 , 39 , 40 , 67 , 75 , 76 , 86 , 98 , 115 Iran (n = 1), 87 Italy (n = 5), 22 , 24 , 43 , 46 , 91 Ivory Coast (n = 1), 13 Japan (n = 2), 57 , 106 Mexico (n = 1), 45 Nepal (n = 1), 28 Pakistan (n = 2), 62 , 97 Poland (n = 1), ...…”

“…The characteristics of study population were heterogeneous among studies. According to the clinical presentations, etiology of liver diseases, patients’ conditions, and treatment options, they were mainly classified as follows: patients presenting with acute gastrointestinal bleeding (n = 12), 14 , 15 , 26 , 45 , 57 , 69 , 81 , 84 , 89 , 94 , 109 , 117 patients presenting with ascites (n = 2), 65 , 96 patients presenting with HE (n = 1), 10 patients presenting with acute-on-chronic liver failure (ACLF) (n = 5), 40 , 58 , 86 , 119 , 128 patients presenting with infection, sepsis, or spontaneous bacterial empyema (n = 5), 30 , 62 , 72 , 73 , 116 patients admitted to intensive care unit (ICU) (n = 10), 34 , 37 , 42 , 71 , 78 , 80 , 107 , 108 , 110 , 112 patients with trauma (n = 2), 35 , 93 patients with viral hepatitis-related liver cirrhosis alone (n = 3), 27 , 56 , 79 patients with alcohol-related liver cirrhosis alone (n = 5), 19 , 61 , 70 , 75 , 120 patients undergoing TIPS (n = 8), 11 , 31 , 44 , 91 , 92 , 101 , 113 , 123 patients undergoing LT (n = 10), 23 , 38 , 41 , 48 ...…”

“…As for the meta-analysis, 77 papers were excluded, 12 , 14 – 16 , 20 – 23 , 26 – 31 , 33 – 39 , 41 , 43 – 47 , 49 – 51 , 53 – 55 , 57 – 60 , 63 , 64 , 66 , 68 – 73 , 75 , 78 , 79 , 81 – 83 , 85 , 86 , 88 – 90 , 92 , 93 , 95 , 96 , 99 – 101 , 103 , 105 , 106 , 113 , 114 , 118 , 120 – 124 , 126 , 128 because 76 studies were lacking of relevant data 12 , 14 – 16 , 20 – 23 , 26 – 31 , 33 – 39 , 41 , 43 – 47 , 49 – 51 , 53 – 55 , 57 – 59 , 63 , 64 , 66 ,…”

Nomogram to Predict the Survival of Chinese Patients with Alcohol-Related Liver Disease

“…After that, MELD score was extended to assess the mortality of end-stage liver disease and assist liver transplantation centres in organ allocation [11]. In previous studies, MELD score was shown to have a good predictive value for the survival of patients with AH [33][34][35]. In our study, we used an MELD score of ≥21 as the cutoff point and applied it to the overall ALD population.…”

Shock Index, Modified Shock Index and MELD as Predictors of Mortality for Critically Ill Patients With Liver Disease

“…3 The Model for End Stage Liver Disease (MELD) score was first described in 2001 as a predictor of 3 month mortality in patients with cirrhosis. 4 MELD has been shown to be a predictor of mortality in patients with acute alcoholic hepatitis, 5 alcoholic liver disease, 6 and esophageal variceal bleeding. 7 It also is used for allocation of donor livers for patients on the liver transplant list.…”