Retrospective Analysis of the Effects of Neutrophil / Lymphocyte Ratio on Intraoperative Acidosis Development and Hospitalization Time in Patients Underwent Radical Robotic Prostatectomy

Abstract

Objective: This study aimed the predictive value of the neutrophil to lymphocyte ratio (NLR) for intraoperative acidosis and postoperative lenght of hospital stay in patients undergoing robotic assisted radical prostatectomy procedure. Material and Methods: Patients with locally advanced prostate cancer undergoing elective robotic assisted radical prostatectomy procedure were included in the study. Inclusion criteria was being ASA I-II, and receiving sugammadex for recovery of neuromuscular block. Complete blood counts and blood-gas analyses were performed perioperatively. The neutrophil to lymphocyte ratio was calculated by dividing neutrophil counts to lymphocyte counts. Acidosis was defines as pH levels below 7.35. Results: A total of forty-six patients (mean age 64.06±6.4 years) were included. Blood gas changes were detected in twenty three patients. Eighteen patients in the study population had combined acidosis. Twelve patients had acidosis according to pH levels, seven patients had PaCO2 ≥ 45 mmHg, and seven patients had Lactate ≥1.6 mmol/L. Median hospital stay was five days (0-10 days). NLR levels were not found to be significantly different between the groups, and were not correlated with patient age (p=0.907) or duration of hospital stay (p=0.654). Conclusion: NLR was not found to be a marker for acidosis or predictive of prolonged hospital stay in patients undergoing the RARP procedure.