Retrospect

Powder Suspension Method for Critically Re-Examining the Two-Site Model for Hydroxyapatite Dissolution Kinetics

“…Keyphrases 0 Microspheres-polyacrylamide, phagocytosis by cultured mouse peritoneal macrophages, ultrastructural cellular alterations 0 Macrophages, peritoneal-cultured from mice, effect of phagocytosis of microparticles, ultrastructural cellular alterations Phagocytosismicroparticles, by cultured mouse peritoneal macrophages, ultrastructural cellular alterations Acrylic polymer microparticles have been introduced recently as carriers for enzymes and other macromolecules (1). When such particles are injected intravenously into mice and rats they are eliminated rapidly from the circulatory system, mainly by the fixed macrophages of the reticuloendothelial system (RES) (2), and accumulate intracellularly within the lysosomal vacuome of these cells (3).…”