Retroperitoneal unicentric Castleman's disease with multiple lymph node involvement

Schulte, Klaus–Martin; Sinha, Prakash; Talat, Nadia; Díaz‐Cano, Salvador

doi:10.1136/bcr.03.2011.3938

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…Recently, some authors has demonstrated surgical cure by oncological resection. Schulte et al 16 reported that if possible oncological resection must be performed for disseminated CD. When complete resection is impossible, palliative resection or radiotherapy may be used to control possible systemic manifestations 4,9 .…”

Section: Discussionmentioning

confidence: 99%

Unicentric retroperitoneal Castleman disease: Report of 3 cases

et al. 2015

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SUMMARYCastleman Disease is a rare lymphoproliferative disorder mainly occuring in the mediastinum. Abdominal forms are less frequent and manifests rarely as an isolated retroperitoneal mass. The diagnosis is based on postoperative pathological findings. Herein, we report three cases of unicentric retroperitoneal Castleman Disease from our center. Three women were detected to have a retroperitoneal mass in the medical examinations. The masses were surgically removed and histopathological examination revealed a hyaline-vascular type of Castleman disease. Although retroperitoneal Castleman Disease is rare, it should be considered in the differential diagnosis of retroperitoneal masses. Keywords: Castleman Disease, retroperitoneal mass ÖZET Castleman Hastalığı daha çok mediastinumda görülen nadir bir lenfoproliferatif hastalıktır. Abdominal formları nadir görülürler ve çok nadir olarak izole retroperitoneal bir kitle şeklinde ortaya çıkarlar. Tanı postoperatif patolojik bulgulara göre koyulur. Bildirimizde karşılaştığımız üç unisentrik retroperitoneal Castleman Hastalığı olan hastayı sunduk. Medikal muayeneler sonucu üç kadın hastada retroperitoneal kitle tespit edildi. Kitleler cerrahi olarak çıkarıldı ve histopatolojik inceleme sonucu hiyalin-vasküler tip Castleman Hastalığı tespit edildi. Castleman Hastalığı nadir olmasına rağmen retroperitoneal kitlelerin ayırıcı tanısında düşünülmelidir.

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Section: Discussionmentioning

confidence: 99%

Unicentric retroperitoneal Castleman disease: Report of 3 cases

et al. 2015

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“…Castleman's disease is categorized as hyaline vascular type and plasma cell type by histology [ 6 ]. By involved solitary or multiple lymph node sites, Castleman's disease is classifi ed as unicentric and multicentric diseases [ 7 ]. Hyaline vascular type of retroperitoneal Castleman's disease typically shows homogeneous density and homogeneous moderate to strong enhancement on computed tomography (CT), as well as hypointense on T1-weighted image and hyperintense on T2-weighted image on magnetic resonance imaging (MRI) [ 6 , 7 ].…”

Section: Key Diagnostic Featuresmentioning

confidence: 99%

Retroperitoneal Diseases

Wang¹

2014

Key Diagnostic Features in Uroradiology

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Retroperitoneal hyaline-vascular variant Castleman Disease in a patient with iron-deficiency anemia and sinus bradycardia: a case report

Guo

Zhu

et al. 2017

Oncology and Translational Medicine

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ObjectiveCastleman disease, also known as giant lymph node hyperplasia, involves lesions in the lymph nodes usually located in the chest_ENREF_1, particularly in the mediastinum. Meanwhile, sinus bradycardia is a sinus rhythm slower than 60 beats per min, and it can occur in both healthy and sick individuals. However, the comorbidity of these two disorders has not been previously reported. In this paper, we report a case of a 46-year-old woman who presented with persistent sinus bradycardia and iron-deficiency anemia. Diagnostic work-up revealed hepatosplenomegaly and a giant mass near the splenic hilum. The mass was removed surgically; after which, the patient's bradycardia resolved immediately, while her anemia was corrected after subsequent chemotherapy. Pathological examination revealed lymph nodes with benign lesions, and the patient was diagnosed with hyaline-vascular variant of Castleman disease. This is the first documented case of sinus bradycardia associated with Castleman disease. In this paper, we describe the case characteristics, discuss the possible pathogenesis, and consider the appropriate treatment of symptomatic sinus bradycardia accompanying Castleman disease.

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Retroperitoneal unicentric Castleman's disease with multiple lymph node involvement

Cited by 4 publications

References 8 publications

Unicentric retroperitoneal Castleman disease: Report of 3 cases

Unicentric retroperitoneal Castleman disease: Report of 3 cases

Retroperitoneal Diseases

Retroperitoneal hyaline-vascular variant Castleman Disease in a patient with iron-deficiency anemia and sinus bradycardia: a case report

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