Retroperitoneal mesenchymal chondrosarcoma with metastasis to iliac vein: A rare case report and review of the literature

Abstract

The iliac vein is an extremely rare site of metastasis for extraskeletal mesenchymal chondrosarcoma (ESMC). Involvement of the veins usually leads to an extremely dismal prognosis. Here, we report a 50-year-old patient with retroperitoneal mesenchymal chondrosarcoma and initial metastasis to the iliac bone, which further progressed to involve the iliac vein. In this study, we reviewed the major characteristics of ESMC and the previously reported cases, considering the rarity of these tumors.

Mesenchymal Chondrosarcoma from Diagnosis to Clinical Trials

“…The sites most frequently affected by EMC are the head and neck, followed by the lower extremities. However, there are rare reports of EMC involving various soft tissue and visceral locations [ 10 ], but the female genitalia, kidneys, pancreas, chest wall, and retroperitoneal space are rare sites of origin for EMC [ 11 , 12 ]. A study conducted in 2021 at the Department of Radiology of the Memorial Sloan Kettering Cancer Center in New York included 23 patients (average age 28 ± 6 years) presenting 13 skeletal and 10 EMCs.…”