Retroperitoneal Laparoscopic
Nephrectomy in Children

Valla, Jean Stéphane; B, Guilloneau; Montupet, Philippe; Geiss, S; Steyaert, Henri; El-Ghoneimi, Alaa; Jordana, F; Volpe, Paula

doi:10.1159/000474221

Cited by 43 publications

(23 citation statements)

References 19 publications

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“…A retroperitoneal chamber is created with either balloon dissection or a simple dissection using the tip of the laparoscope and pneumodissection. In general, two more trocars are used for triangulation [30,33].…”

Section: Methodsmentioning

confidence: 99%

Current indications for laparoscopy and retroperitoneoscopy in pediatric urology

2004

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Laparoscopy has raised great interest in the past few years in the field of pediatric urology. It has evolved from a simple diagnostic maneuver to complex operative procedures. The aim of this study was to review urologic laparoscopy literature and provide a critical review of this field to establish current indications for videosurgery in pediatric urology. In general, from an anatomic point of view, retroperitoneoscopy seems to be more suitable than the transperitoneal laparoscopic approach for reaching the upper urinary tract. It also is less invasive and complies with the criteria for open renal surgery. With respect to current indications for videosurgery in pediatric urology, the authors have identified several well-established clinical procedures, although no large series have been published for any of the procedures, except for the treatment of varicocele, nonpalpable testis, and nephrectomy. In conclusion, the data reviewed suggest that videosurgery is a safe and feasible technique in pediatric urology if performed by expert surgeons, and that it certainly will develop further in the next few years.

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Section: Methodsmentioning

confidence: 99%

Current indications for laparoscopy and retroperitoneoscopy in pediatric urology

2004

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“…2 After unilateral nephrectomy, the remaining kidney undergoes structural and functional changes as a pliant response to quench the increased functional demand to maintain the homeostasis of fluid and solutes in the body. 3,4 The compensatory renal hypertrophy causes an increase in weight and/ or volume of the remaining kidney of the adult animals.…”

Section: Introductionmentioning

confidence: 99%

Ultrastructural changes and nestin expression accompanying compensatory renal growth after unilateral nephrectomy in adult rats

Eladl

Elsaed

Atef

et al. 2017

IJNRD

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Background: Several renal disorders affect the glomerular podocytes. Compensatory structural and functional changes have been observed in animals that have undergone unilateral renal ablation. These changes occur as a pliant response to quench the increased functional demand to maintain homeostasis of fluid and solutes. Nestin is an intermediate filament protein present in the glomerular podocytes of the adult kidney and is linked with the maintenance of its foot process structure. Structural changes in the podocytes ultimately restructure the filtration barrier. Very few studies related to the ultrastructural and histopathologic changes of the podocytes are documented. The present study aimed to assess the histopathologic changes at the ultrastructural level in the adapted kidney at different time intervals following unilateral renal ablation in adult rats and its relation with nestin. Methods: Forty-eight rats were divided into four groups (n=12 in each group). The animals of Group A were control naïve rats, while the group B, group C and group D animals underwent left unilateral nephrectomy and the remaining right kidney was removed on days 10, 20 and 30, respectively. Each group included four sham-operated rats, which were sacrificed at the same time as the naïve rats. Each nephrectomized sample was weighed and its sections were subjected to hematoxylin and eosin examination, transmission electron microscopic study as well as immunostaining using the intermediate filament protein nestin. Results: No difference was found between the kidney sections from the control group and the sham-operated groups. A significant increase in the weight of the right kidneys was noted in groups B, C and D (P<0.001). The ultrastructural adaptive changes seen in the glomeruli of group B were subsequently reduced in groups C and D. This finding corresponded to a similar pattern of nestin expression in the podocytes, which showed significant increase in group B followed by reduced expression in groups C and D. Histopathologic and transmission electron microscopic evaluation of group B showed signs of kidney injury. On the other hand, group C animals showed markedly reduced renal adaptive changes and similar changes were also noted in group D. Conclusion: Correlation between nestin expression and the ultrastructural changes confirms that nestin has a role in increasing the mechanical stability of the podocytes in order to enhance their morphologic changes in response to the tensile glomerular capillary wall. However, further studies investigating more remote ultrastructural changes and their relation with nestin expression are needed to confirm this relationship.

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“…In a retrospective study of 63 patients, elimination of CO 2 was assessed and it was observed that its absorption is higher in patients treated through an extraperitoneal approach, especially those with subcutaneous emphysema. However, there were no significant sequelae of hypercapnia [14,42,44].…”

Section: Discussionmentioning

confidence: 89%

“…100% success of RPN in various series, irrespective of a learning curve, is an indirect testimony of the establishment of this technique [26,40,41,45,[48][49][50]. Other authors have reported successful RPN in nearly 90% of cases [19,21,31,42,47,52,54] except one where the success rate was about 85% [52]. The conversions may be on account of a learning curve, improper selection of cases in the initial period and technical difficulties.…”

Section: Resultsmentioning

confidence: 99%

Retroperitoneoscopic Nephrectomy for Benign Diseases of the Kidney

Hemal¹

2001

Urol Int

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Retroperitoneal Laparoscopic Nephrectomy in Children

Cited by 43 publications

References 19 publications

Current indications for laparoscopy and retroperitoneoscopy in pediatric urology

Current indications for laparoscopy and retroperitoneoscopy in pediatric urology

Ultrastructural changes and nestin expression accompanying compensatory renal growth after unilateral nephrectomy in adult rats

Retroperitoneoscopic Nephrectomy for Benign Diseases of the Kidney

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