Retroperitoneal Extragastrointestinal Stromal Tumor: Radiologic Pathologic Correlation

Watal, Pankaj; Brahmbhatt, Swetang G; Thoriya, Prashant J; Bahri, Nandini

doi:10.4103/2156-7514.135484

Cited by 8 publications

(11 citation statements)

References 7 publications

(17 reference statements)

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“…Similar imaging features may be seen in lymphomas and other mesenchymal tumors in the same location; however, the differentiation from EGISTs on imaging may be made on the basis of absence of necrosis, cystic changes, hemorrhage and calcification within lymphomatous neoplasms [ 19 , 20 ]. Even though the tumor in our case did not demonstrate any calcification within it, calcification within these tumors has been described in few reports in literature [ 4 , 6 ]. Calcification is rare in untreated lymphoma of the retroperitoneum [ 21 ].…”

Section: Discussioncontrasting

confidence: 64%

“…Calcification is rare in untreated lymphoma of the retroperitoneum [ 21 ]. The tumor size in our patient was less than 10 cm in its largest dimension, which is an interesting observation compared to large malignant GISTs (average size more than 7 cm) in previously demonstrated studies [ 3 , 4 , 22 ]. No other metastatic lesion was demonstrated on imaging.…”

Section: Discussionsupporting

confidence: 58%

“…A distant theory also suggests that in effect, EGISTs may be an extramural extension of stromal tumors within the GIT [ 3 ]. Characteristic similarities and differences between the two entities have been listed in Table 1 [ 1 , 4 , 5 , 7 , 12-18 ].…”

Section: Discussionmentioning

confidence: 99%

“…Of the three sub-types of EGISTs, the retroperitoneal EGIST is the rarest. A handful of less than 70 cases of retroperitoneal EGISTs have been reported in English literature, so far, to the best of our knowledge [ 3 , 4 ]. In the following case study, the patient was managed with chemotherapy using imatinib mesylate, since the tumor was unresectable.…”

Section: Introductionmentioning

confidence: 99%

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Malignant Retroperitoneal Extra-Gastrointestinal Stromal Tumor: A Unique Entity

et al. 2016

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Extra-gastrointestinal stromal tumors (EGISTs) are a recently described group of tumors. A handful of less than 70 cases have been reported in English literature, so far, to the best of our knowledge. Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the alimentary canal. EGISTs are a unique entity, which require distinction from GISTs because, even though, they exhibit similar histology and immunohistochemistry to GISTs, they occur outside the gastrointestinal tract, i.e. in omentum, mesentery, retroperitoneum, etc. and have different behavior patterns as far as their prognosis and management are concerned. Retroperitoneal sub-group of EGISTs is extremely rare and we report such a case of primary malignant EGIST of the retroperitoneum which presented as a soft tissue mass on radiological evaluation. The tumor turned out to be a histopathological surprise, and could be distinctively labeled as EGIST only after morphological and immunohistochemical studies. It is imperative for radiologists, pathologists and oncologists, among other clinicians, to be able to recognize and understand the presentation of this group of tumors due to their rapid progression and poor prognosis, so that an early diagnosis and management may be able to improve the final disease outcome.

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Section: Discussioncontrasting

confidence: 64%

Section: Discussionsupporting

confidence: 58%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Malignant Retroperitoneal Extra-Gastrointestinal Stromal Tumor: A Unique Entity

et al. 2016

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“…[ 25 ] On cross-sectional imaging, retroperitoneal EGISTs are mostly seen as well-defined, inhomogeneous, soft-tissue masses with heterogeneous contrast enhancement. However, they are seldom seen as homogeneous mass lesions[ 26 ] [ Figure 12 ].…”

Section: Malignant Mesodermal Tumorsmentioning

confidence: 99%

Cross-sectional Imaging Features of Primary Retroperitoneal Tumors and Their Subsequent Treatment

Acar

Harman

Güneyli

et al. 2015

Journal of Clinical Imaging Science

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Basically malignant tumors in the retroperitoneal region arise from a heterogeneous group of tissues: mesodermal, neurogenic, germ cell, and lymphoid. Although rare, benign tumors and cystic masses can be also encountered in retroperitoneal space. Developments in computed tomography (CT) and magnetic resonance imaging (MRI) have contributed to both diagnosis and staging of the retroperitoneal tumors. High spatial resolution and superiority in calcification make CT indispensable; on the other hand, MRI has a better soft-tissue contrast resolution which is essential for the assessment of vascular invasion and tissue characterization. The aim of this article is to review the CT and MRI features of retroperitoneal tumors and their subsequent management.

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Radiological diagnosis of perinephric pathology: pictorial essay 2015

Mitreski

Sutherland

2017

Insights Imaging

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The perinephric space, shaped as an inverted cone, sits between the anterior and posterior renal fasciae. It can play host to a variety of clinical conditions encountered daily in the reporting schedule for a radiologist. Lesions may be classified and diagnosed based on their imaging characteristics, location and distribution. A broad range of differential diagnoses can be attributed to pathology sitting within this space, often without clinical signs or symptoms. An understanding of commonly encountered conditions affecting the perinephric space, along with characteristic imaging findings, can illustrate and often narrow the likely diagnosis. The aim of this essay is to describe commonly encountered neoplastic and non-neoplastic entities involving the perinephric space and to describe their key imaging characteristics.Teaching Point• Despite often a bulky disease, perinephric lymphoma does not produce obstruction or stenosis.• In primarily fatty masses, defects within the renal capsule likely represent angiomyolipoma.• Consider paraganglioma if biopsy is planned; biopsy may lead to catecholamine crisis.

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Retroperitoneal Extragastrointestinal Stromal Tumor: Radiologic Pathologic Correlation

Cited by 8 publications

References 7 publications

Malignant Retroperitoneal Extra-Gastrointestinal Stromal Tumor: A Unique Entity

Malignant Retroperitoneal Extra-Gastrointestinal Stromal Tumor: A Unique Entity

Cross-sectional Imaging Features of Primary Retroperitoneal Tumors and Their Subsequent Treatment

Radiological diagnosis of perinephric pathology: pictorial essay 2015

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