Retroperitoneal Castleman’s Disease

Abstract

Castleman’s disease was first reported in 1954 by Castleman et al. and identified as an uncommon lymphoproliferative disorder. In most cases, Castleman’s diseases are detected in the chest, head, and neck. A 71-year-old man was referred to our hospital due to a retroperitoneal tumor in the para-aortic area by computed tomography (CT). Positron emission tomography-CT revealed an uptake in this tumor, suggesting malignant diseases. Laparoscopic tumorectomy was performed, and the pathological diagnosis was Castleman’s disease, hyaline vascular type. No evidence of recurrence was observed 20 months after surgery. We herein report a rare case of retroperitoneal Castleman’s disease.

Castleman Hastalığı: Laparoskopik yaklaşımla tedavi edilen pararenal alanda nadir bir retroperitoneal kitle

“…Diagnosis can only be confirmed with postoperative pathology [2]. In all types of Castleman disease, surgery is required for differential diagnosis [6]. Our patient presented with back pain on right side and abdominal discomfort.…”

Castleman's disease: Laparoscopic resection of unicentric disease in the hepatic hilum: A case report

“…The hyaline vascular type is the most common and is characterized by follicular hyperplasia and its germinal centers exhibiting capillaries with hyaline matter [ 3 , 5 ]. All three variants present can present clinically with lymphadenopathy or systemic symptoms [ 3 , 6 ].…”

“…Even though UCD is not a malignant condition but many dangerous tumors, including Non-Hodgkin lymphoma, paraganglioma, leiomyoma, leiomyosarcoma, fibrosarcoma, and amyloidosis, have been associated with it [ 3 , 5 ]. The differential must also include diseases with lymphadenopathy, including tuberculosis, lymphadenitis, abscess, sarcoidosis, HIV, toxoplasmosis, among others [ 1 , 3 , 6 ]. In our patient, as the mass was discovered in an area of major vascular structures and had contrast enhancement, surgery was decided instead of a biopsy to prevent complications.…”

Pénfigo paraneoplásico como presentación atípica de la enfermedad de Castleman

“…Las localizaciones más frecuentes a nivel de la economía corporal en la EC son torácicas (60%), cervical (14%), abdominal (11%) y axilar (4%) (8). En nuestro caso específico encontramos la ubicación de la lesión tumoral prominente estaba en retroperitoneo, que no constituye una de las localizaciones más habituales, siendo aproximadamente el 3%, pero el subtipo histológico encontrado fue HV que es el más frecuente en la mayoría de series revisadas como es el caso de Kawamura et al (9) quienes informaron que subtipo HV se encontró en 87% de 132 casos de enfermedad de Castleman retroperitoneal en población japonesa.…”