Retroperitoneal and scrotal giant liposarcoma: Report of a case

Yol, Serdar; Tavlı, Şakir; Tavlı, Lema; Belviranlı, Metin; Yosunkaya, Alper

doi:10.1007/s005950050136

Cited by 41 publications

(37 citation statements)

References 10 publications

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“…Previously, only a few published case reports of inguinal hernia were available, and they discussed an LPS protruding from the retroperitoneum. [4][5][6][7][8][9]12,13 Although 6 is a small number for reliable statistical analysis, we showed that RLPS protruding into the inguinal canal has poor prognosis compared with inguinoscrotal LPS.…”

Section: Discussionmentioning

confidence: 99%

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Comparison of retroperitoneal liposarcoma extending into the inguinal canal and inguinoscrotal liposarcoma

Rhu

Cho

Lee

et al. 2017

CJS

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Background:This study was designed to analyze differences between retroperitoneal liposarcoma (RLPS) extending into the inguinal canal and inguinoscrotal liposarcoma. Methods:We retrospectively reviewed the records for patients who were managed for inguinal liposarcoma at Samsung Medical Center, a tertiary hospital, between January 1998 and December 2016. Patient data on demographics, tumour location, surgery, adjuvant therapy, histology, recurrence and death were collected. We used Mann-Whitney, Fisher exact and Kaplan-Meier log-rank tests to analyze differences between groups.Results: Seven of 179 (3.9%) patients with abdominal liposarcoma had inguinoscrotal liposarcoma, and 6 of 168 (3.6%) patients with RLPS had extension to the inguinal canal. No differences were observed between groups in sex (p > 0.99), mean age (49.7 ± 6.4 yr v. 52.1 ± 12.5 yr, p = 0.37), laterality (p > 0.99) or scrotal involvement (40.0% v. 66.7%, p = 0.57). The RLPS group had significantly larger tumours than the inguinoscrotal group (27.9 ± 6.8 cm v. 7.8 ± 4.2 cm, p = 0.001). Postoperative complications were significantly more common in the RLPS group (n = 4, 83.3%); patients in the inguinoscrotal group experienced no postoperative complications (p = 0.021). Log-rank tests showed that the groups had no statistical differences in diseasefree survival (p = 0.94) or overall survival (p = 0.10). However, inoperable disease-free survival was significantly poorer in the RLPS group (p = 0.010). Conclusion:Although initial signs and symptoms can be similar, RLPS extending into the inguinal canal was associated with significantly higher morbidity and mortality than inguinoscrotal liposarcoma.Contexte : Cette étude visait à examiner les différences entre le liposarcome rétro-péritonéal s'étendant au canal inguinal et le liposarcome inguino-scrotal.Méthodes : Nous avons procédé à une analyse rétrospective des dossiers de patients traités pour un liposarcome inguinal au Samsung Medical Center, un hôpital de soins tertiaires, entre janvier 1998 et décembre 2016. Nous avons recueilli les données des patients en ce qui a trait aux caractéristiques démographiques, au siège de la tumeur, à la chirurgie, au traitement adjuvant, à l'histologie, à la récidive et au décès. Nous avons utilisé le test de Mann-Whitney, la méthode exacte de Fisher et les tests logarithmiques par rangs de Kaplan-Meier pour analyser les différences entre les 2 groupes.Résultats : Sept des 179 (3,9 %) patients atteints de liposarcome abdominal avaient un liposarcome inguino-scrotal, et 6 des 168 (3,6 %) patients atteints de liposarcome rétropéritonéal présentaient une extension au canal inguinal. Aucune différence n'a été observée entre les groupes pour le sexe (p > 0,99), l'âge moyen (49,7 ± 6,4 ans c. 52,1 ± 12,5 ans, p = 0,37), la latéralité (p > 0,99) ou l'atteinte scrotale (40 % c. 66,7 %, p = 0,57). La taille de la tumeur était significativement plus grande dans le groupe du liposarcome rétropéritonéal que dans celui du liposarcome inguino-scrotal (27,9 ± 6,8 cm c. 7,8 ± ...

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Section: Discussionmentioning

confidence: 99%

“…Only a few case reports describe RLPS presenting as an inguinal hernia. [4][5][6][7][8][9] Sometimes, a protruding mass in the inguinal region is the only symptom, resulting in a misdiagnosis of ordinary inguinal hernia.…”

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confidence: 99%

Comparison of retroperitoneal liposarcoma extending into the inguinal canal and inguinoscrotal liposarcoma

Rhu

Cho

Lee

et al. 2017

CJS

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“…This disease may metastasize, and this most frequently affects the lungs and liver. The complementary imaging examinations used are computed tomography, magnetic resonance and angiography, but the diagnosis is made only from the anatomopathology (10,13) .…”

Section: Discussionmentioning

confidence: 99%

Lipossarcoma de joelho em um atleta de tênis: relato de caso

Filho¹,

Sayum²,

Carvalho³

et al. 2012

Rev. bras. ortop.

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CASE REPORTThe patient was a 40-year-old white man who was an amateur tennis player. He came to the orthopedics and traumatology outpatient clinic at the Assunção Hospital and Maternity Hospital, in São Bernardo do Campo, São Paulo, presenting tumor formation in his right lower limb that had started around one year earlier, with gradual progression. He said that he had not had any other symptoms such as pain, fever, nausea or weight loss.On physical examination, he presented a good general state and was eutrophic, not jaundiced, not cyanotic and not febrile. On orthopedic examination, he presented painless tumor growth on the posterior face of the right knee and distal thigh, with fibroelastic consistency and without any temperature difference.Radiographs of the knee were requested and showed increased soft-tissue volume. Ultrasound showed a mass of solid appearance measuring 15 x 20 cm. Because of this, computed tomography and magnetic resonance imaging were requested to assess the tumor formation better. At that time, it was suspected that the diagnosis could be liposarcoma and therefore imaging examinations were requested for staging purposes (radiographs on the lungs, bone scintigraphy, PET SCAN and tomography on the chest, abdomen, pelvis and cranium). These were found to be normal (Figures 1 to 3).With these findings, surgical treatment was scheduled (radical tumor excision). During the operation, a tumor measuring 18 x 20 cm was removed, and this was sent for anatomopathological analysis (Figures 4 and 5).The anatomopathological diagnosis was that this was a case of myxoid liposarcoma, with free margins. The oncologist who was following up the case with the orthopedist advised that adjuvant radiotherapy should be administered, and this was done (Figure 6).Two years after the operation, the patient is asymptomatic (without recurrence or metastasis) and is continuing to practice tennis. DISCUSSIONSarcomas are rare tumors and originate from primitive mesenchymal cells. They account for 0.1 to 0.2 % of all cases of neoplasia in adults (1)(2)(3) .

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“…2 But giant retroperitoneal liposarcomas are very rare malignancy. Till now largest retroperitoneal liposarcoma was reported to be 42kg by Yol S et al 9 Non-specific abdominal pain and discomfort or a palpable abdominal mass with increased abdominal girth is the common presentation accompanying with anorexia, cachexia. The symptoms are often due to compression of adjacent structures (organs) by the enlarged tumour mass.…”

Section: Discussionmentioning

confidence: 99%