Retrolental Fibroplasia: A Survey*

Genetic susceptibility to retinopathy of prematurity: the evidence from clinical and experimental animal studies

“…Ethnicity was first identified as a significant influence on ROP in 1952, when Zacharias published her observation that in several cohorts of premature infants in the USA, black infants were less likely to develop retinopathy than white infants 19. Other investigators,13 16 20 26 including those involved in the CRYO-ROP cohort of 4099 premature infants and a British study of 505 such babies, have since confirmed a reduced risk of severe ROP in black infants compared with white infants, at least in North American and British populations.…”

Etiology of Retrolental Fibroplasia

“…It has appeared from many reports that retrolental fibroplasia is related to the administration of oxygen or its sudden with¬ drawal. These reports are discussed in the exhausive reviews by Zacharias, 10 Maumenee,f and Wagener.13 It also has been shown in recent years that the disease can be largely prevented by curtailing the amount of oxygen given. * References 8 and 9. \ s=d\ References 11 and 12. .…”

Chapter VI: The Visually Handicapped

“…The amazing strides of modern medicine in saving and prolonging life have resulted in an increasing number and incidence or individuals with impaired vision (2,11,89,104). This is a challenge of tremendous import to education.…”