Retransplant Due to Fulminant Hepatic Failure From Hepatitis E Virus: A Case Report

González, E Tenorio; Díaz, Mireia; Jimenez, Roxanna; Grande, Rocío González; Martín, Raúl Vicente Olmedo; López, J.M. Rodrigo; Pérez, Miguel Jiménez

doi:10.1016/j.transproceed.2017.09.059

Cited by 4 publications

(1 citation statement)

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“…In a longitudinal study performed in Cordoba in HIV patients it was found that living in a rural habitat was a risk factor for HEV seroconversion having 0.8% (5/627) of the patients seroconverted for IgM anti-HEV and 5.7% (36/627) for IgG anti-HEV (A Rivero-Juarez et al, 2017b ). One study from Málaga, reporting a retransplant due to fulminant hepatic failure due to HEV infection in a patient, found a seroconversion for both anti-HEV antibodies, IgM and IgG (Tenorio González et al, 2018 ). In the study of Galicia, that described an acute meningitis secondary to autochthonous HEV-3 infection in an immunocompetent patient, the serologic acute phase marker, IgM anti-HEV was also detected (Rodríguez-Castro et al, 2018 ).…”

Section: Resultsmentioning

confidence: 99%

Hepatitis E Virus in the Iberian Peninsula: A Systematic Review

et al. 2023

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One of the most frequent causes of acute viral hepatitis is hepatitis E virus (HEV) causing 20 million infections worldwide each year and 44,000 deaths. Studies on HEV in the Iberian Peninsula have been increasing through time with HEV infection being identified in humans and animals. The aim of the present systematic review was to compile and evaluate all the published data on HEV from studies performed in humans, animals and environmental samples in the Iberian Peninsula. The electronic databases Mendeley, PubMed, Scopus, and Web of Science were thoroughly searched, and research published up until February 01, 2023 were included. Resulting in a total of 151 eligible papers by full reading and application of PRISMA exclusion/inclusion criteria. Overall, the present review shows that several HEV genotypes, namely HEV-1, 3, 4, and 6 as well as Rocahepevirus, are circulating in humans, animals, and in the environment in the Iberian Peninsula. HEV-3 was the most common genotype circulating in humans in Portugal and Spain, as expected for developed countries, with HEV-1 only being detected in travelers and emigrants from HEV endemic regions. Spain is the biggest pork producer in Europe and given the high circulation of HEV in pigs, with HEV-3 being primarily associated to zoonotic transmission through consumption of swine meat and meat products, in our opinion, the introduction of an HEV surveillance system in swine and inclusion of HEV in diagnostic routines for acute and chronic human hepatitis would be important. Additionally, we propose that establishing a monitoring mechanism for HEV is crucial in order to gain a comprehensive understanding of the prevalence of this illness and the various strains present in the Iberian Peninsula, as well as their potential impact on public health.

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Section: Resultsmentioning

confidence: 99%