[Retracted] Value of Multislice Spiral CT in Differential Diagnosis of Thick‐Wall Gallbladder Carcinoma and Chronic Cholecystitis

Abstract

To summarize the value of multislice spiral CT (MSCT) in the differential diagnosis of thick-wall gallbladder carcinoma (TWGC) and chronic cholecystitis (CC), the clinical data of 36 patients with TWGC and 60 patients with chronic cholecystitis who were treated in our hospital from January 2017 to May 2021 were retrospectively analyzed, and the CT image features and diagnostic accuracy of the patients were summarized. Compared with the CC group, the proportions of disruption of gallbladder mucosa line, blurred gallbladder outline, high obstruction of biliary tract, lymphomegaly, adjacent invasion, peritoneal effusion, wall nodules, and the gallbladder wall thickness in the TWGC group were higher, with statistical significance ( P < 0.05 ). Thirty-four patients with TWGC and 62 patients with chronic cholecystitis were diagnosed by MSCT. The sensitivity and specificity of MSCT in diagnosing TWGC were 86.11% and 95.00%, respectively. The positive likelihood ratio was 17.222 and the negative likelihood ratio was 0.1462. The positive prediction rate was 91.18%, the negative prediction rate was 91.94%, and the correct rate was 91.67%. MSCT can show the characteristic difference between TWGC and chronic cholecystitis, which can be used for differential diagnosis.

Gallbladder Cancer: Diagnosis and Surgical Management

“…Common CT imaging findings for GBCa include GB wall thickening, evidence of an isolated hypodense intraluminal mass, GB wall calcification, and porcelain GB. CT imaging is also especially helpful in identifying infiltration of surrounding organs, LN involvement, peritoneal nodules, and distant metastasis [18,19]. MRI of the abdomen can also be used to diagnose GBCa, which is seen as an irregular, hypointense lesion on T1-weighted images and hyperintense lesion on T2-weighted images.…”

“…The TOPAZ-1 trial confirmed the safety and efficacy of Durvalumab plus Gem-Cis, demonstrating improved overall survival versus placebo plus chemotherapy (estimated 24-month was 24.9% vs. 10.4%). Moreover, it showed improvements in prespecified secondary end points including objective response rate up to 26.7% vs. 18 TOPAZ-1 trial was designed to address a locally advanced-unresectable or metastatic population of biliary tract cancer-among which approximately 25% represented GBca-with previously untreated disease but included patients who developed recurrent disease more than 6 months after surgery with curative intent and more than 6 months after the completion of adjuvant therapy [77].…”

Retracted: Value of Multislice Spiral CT in Differential Diagnosis of Thick-Wall Gallbladder Carcinoma and Chronic Cholecystitis

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”