RETRACTED: Validation of the Aldosteronoma Resolution Score as a Predictive Resolution Score of Hypertension After Unilateral Adrenalectomy for Primary Aldosteronism in a North‐African Population

Abstract

Background Unilateral primary aldosteronism (UPA) is the most frequent surgically curable form of endocrine hypertension. Adrenalectomy is the cornerstone of treatment for UPA, but outcomes after surgery are variable. Aldosteronoma Resolution Score (ARS) is a four-item predictive score for the cure of hypertension after adrenalectomy for UPA and has been demonstrated to be valid in different populations. We aimed in this study to validate the accuracy of this score in a North-African population. Methods Between 2000 and 2021, the charts of 71 Tunisian patients who underwent laparoscopic adrenalectomy for UPA were retrospectively reviewed. Postoperative outcomes were assessed using the primary aldosteronism surgical outcome (PASO) criterion. The accuracy of the ARS was determined retrospectively by receiver operating characteristic curve and area under the curve. Results Thirty-four patients (48%) had complete clinical success according to the PASO criteria. Multivariate regression analysis revealed that the main determinants of complete clinical success were the absence of diabetes (OR: 5.205), a BMI \30 (OR: 4.930), a number of antihypertensive medications B2 (OR: 8.667), a plasma ARR [332 (OR: 4.554) and an ARS score C3 (OR: 2.056). Cure rates were, respectively, 21.1, 51.6, and 66.6% for patients with a score ARS 0-1, 2-3, and 4-5. The AUC of the ARS was 0.837. ConclusionThe ARS is a sufficiently predictive score in our North-African population. It may be used preoperatively to predict the outcome after adrenalectomy in these populations.

Letter to the Editor: Validation of the aldosteronoma resolution score as a predictive resolution score of hypertension after unilateral adrenalectomy for primary aldosteronism in a North‐African population

“…Dear Editor, I am writing in response to the article "Validation of the Aldosteronoma Resolution Score as a Predictive Resolution Score of Hypertension After Unilateral Adrenalectomy for Primary Aldosteronism in a North-African Population" by Ahmed Saaid et al, recently published in WJS. 1 The study validates the aldosteronoma resolution score (ARS) in a North-African population, providing valuable insights into the predictability of hypertension cure after adrenalectomy for unilateral primary aldosteronism.…”

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Dear Editor, I am writing in response to the article "Validation of the Aldosteronoma Resolution Score as a Predictive Resolution Score of Hypertension After Unilateral Adrenalectomy for Primary Aldosteronism in a North-African Population" by Ahmed Saaid et al, recently published in WJS. 1 The study validates the aldosteronoma resolution score (ARS) in a North-African population, providing valuable insights into the predictability of hypertension cure after adrenalectomy for unilateral primary aldosteronism.The ARS is a four-item predictive score that has been demonstrated to be valid in different populations. 2 However, it is worth noting that there are other prognostic models available, such as the primary aldosteronism surgical outcome score 3 and the Utsumi nomogram.

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