RETRACTED: The effect of prednisolone and/or acyclovir in relation to severity of Bell’s palsy at presentation

Abdelghany, Ahmed Mohammed; Kamel, Samer Badee

doi:10.1016/j.ejenta.2013.04.003

Cited by 10 publications

(5 citation statements)

References 23 publications

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“…These analyses provide useful data for clinicians, but other forms of acute facial paralysis, such as those occurring after parotidectomy 8 were included in the meta‐analyses. Also, results could be confounded through the inclusion of a retracted article 9 and incorrect data extraction 10 . Therefore, we performed a network meta‐analysis to compare all available interventions for the management of Bell's palsy in adults in a single analysis and rank them according to their efficacy.…”

Section: Introductionmentioning

confidence: 99%

Pharmacological Treatments of Bell's Palsy in Adults: A Systematic Review and Network Meta‐Analysis

et al. 2021

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Objective We aimed to simultaneously compare all available medical treatments for Bell's palsy using both direct and indirect data. Methods The literature was searched from January 1, 1990, until March 1, 2020, with no language restrictions. Randomized clinical trials comparing pharmacological interventions were included in the current network meta‐analysis. We estimated summary risk ratios (RRs), 95% credible interval (CrI), and the surface under the cumulative ranking curve (SUCRA) using network meta‐analyses with random effects in a Bayesian framework. The primary outcomes were complete recovery in short‐term (≤3 months) and intermediate/long‐term (>3 months) after randomization. The secondary outcome was synkinesis. Results In total, 21 trials comprising 2,839 participants were retrieved. In terms of good recovery, corticosteroids plus antivirals were the most effective treatment compared to placebo, with RRs ranging between 1.25 (95% CrI: 1.10, 1.43) for the short‐term and 1.26 (95% CrI: 1.11, 1.45) for the intermediate/long‐term recovery. For synkinesis, only corticosteroids plus antivirals (RR 0.35; 95% CrI: 0.19, 0.65) were associated with fewer synkinesis rates than placebo. The certainty of the evidence for good recovery and synkinesis was very low‐low and moderate‐high, respectively. Conclusions This network meta‐analysis showed that combined therapy remains the best regimen for a good recovery outcome and the only efficacious regimen for synkinesis. More research is needed to confirm these findings. Laryngoscope, 131:1615–1625, 2021

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Section: Introductionmentioning

confidence: 99%

Pharmacological Treatments of Bell's Palsy in Adults: A Systematic Review and Network Meta‐Analysis

et al. 2021

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“…5 The current review updates these findings with the inclusion of 10 randomized controlled trials. An 11th randomized controlled trial 6 was initially included in the Cochrane review published earlier 7 ; however, the trial by Abdelghany et al 6 is currently being investigated to determine the reliability of the reported data. As a result, the previous version of the 2015 Cochrane review was withdrawn and the current version was republished, excluding the trial by Abdelghany et al 6 Unfortunately, the quality of evidence included in the current review remains mainly low to moderate.…”

Section: Data Extraction and Synthesismentioning

confidence: 99%

Do Antiviral Medications Improve Symptoms in the Treatment of Bell’s Palsy?

Hernandez

Sherbino

2017

Annals of Emergency Medicine

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“…The authors withdrew the earlier version of the review owing to an ongoing investigation into the reliability of data from one3 of the included studies. Without this study, the review included 10 trials with 2,280 participants, as compared with 11 trials with 2,883 participants in the withdrawn version.…”

Section: Antivirals For Bell's Palsy Revisitedmentioning

confidence: 99%

DTB Select: 2 | February 2016

2016

DTB

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Evidence for fibrates in secondary prevention of CVD ● Impact of comorbidity on benefits of commonly prescribed drugs l Identifying patients at risk of inappropriate prescribing ● Shared decision making to reduce antibiotic prescribing in primary care ● Duration of BCG vaccine protection ● Antivirals for Bell's palsy revisited ● Time to review blood pressure targets? ● Adherence to computerised CBT in primary care ● Collagenase Clostridium histolyticum for Dupuytren's contracture

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RETRACTED: The effect of prednisolone and/or acyclovir in relation to severity of Bell’s palsy at presentation

Cited by 10 publications

References 23 publications

Pharmacological Treatments of Bell's Palsy in Adults: A Systematic Review and Network Meta‐Analysis

Pharmacological Treatments of Bell's Palsy in Adults: A Systematic Review and Network Meta‐Analysis

Do Antiviral Medications Improve Symptoms in the Treatment of Bell’s Palsy?

DTB Select: 2 | February 2016

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