RETRACTED: Reduction of postoperative emetic episodes and analgesic requirements with dexamethasone in patients scheduled for dental surgery

Numazaki, Mitsuko; Fujii, Yoshitaka

doi:10.1016/j.jclinane.2004.06.018

Cited by 30 publications

(21 citation statements)

References 24 publications

(32 reference statements)

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“…In our study, 8 mg dexamethasone had an opioid-sparing effect whereas 4 mg dexamethasone had none. Numazaki and Fujii [25] also found that 8 mg dexamethasone effectively prevented PONV and aided management of postoperative pain compared with 4 mg, and that increasing the dose to 16 mg provided no further benefit, in patients undergoing dental surgery. Fujii and Nakayama [26] also found that 8 mg dexamethasone effectively reduced PONV and analgesic requirement after thyroidectomy.…”

Section: Discussionmentioning

confidence: 97%

Dexamethasone before total laparoscopic hysterectomy: a randomized controlled dose–response study

et al. 2010

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Section: Discussionmentioning

confidence: 97%

Dexamethasone before total laparoscopic hysterectomy: a randomized controlled dose–response study

et al. 2010

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“…[8][9][10][11][12] We did not stratify the risk of significant postoperative pain according to what dental procedures were performed. This may be worth investigating in future studies.…”

Section: Discussionmentioning

confidence: 99%

“…[3][4][5][6] It has also been shown to reduce pain, swelling, and postoperative nausea and vomiting following extraction of third molar teeth in adults. 7,8 Dexamethasone has been shown to reduce postoperative nausea and vomiting in children following strabismus surgery, [9][10][11] especially in combination with ondansetron. 12 We hypothesized that a single intraoperative dose of dexamethasone would reduce postoperative pain and other morbidity in children for up to 24 hr after dental rehabilitation under general anesthesia.…”

Section: Résumémentioning

confidence: 99%

Effect of dexamethasone on postoperative morbidity after dental rehabilitation in children

McIntyre

Hardcastle

Eng

et al. 2011

Can J Anesth/J Can Anesth

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Purpose Dexamethasone reduces postoperative morbidity after adenotonsillectomy, strabismus surgery, and third molar extraction. Our hypothesis was that dexamethasone would reduce pain and other morbidity in children undergoing dental surgery for up to 24 hr postoperatively. Methods A triple-blinded, randomized, controlled trial was carried out on 200 children undergoing prolonged dental rehabilitation under general anesthesia. Subjects were randomized into two groups: group D, given dexamethasone 0.3 mgÁkg -1 ; group S, given normal saline. The primary outcome measure was pain over 24 hr as evaluated by a parental 0-10 numerical rating scale (NRS). Key secondary outcomes included oral intake on a four-point scale at 24 hr and the overall incidence of postoperative vomiting (POV). Analysis for the primary outcome consisted of comparison of means in the NRS with the Wilcoxon rank sum test and for occurrence of POV with Fisher's test. Results After eliminating 22 subjects for protocol violations and withdrawals, 178 subjects were analyzed. There was no significant difference in pain scores (NRS) at 24 hr or the worst NRS experienced over the preceding 24 hr. There was no difference in the quality of oral intake between the groups. There was a significant difference in the percentage of patients who vomited during the first 24 hr: eight of 91 in group S and one of 87 in group D. Therefore, 7.74% more vomited in group S (P = 0.045), with a 95% confidence interval of 0.32 to15.16 for the difference in percentages. Conclusions Dexamethasone, 0.3 mgÁkg -1 , did not reduce pain over 24 hr in healthy children undergoing dental rehabilitation under general anesthesia. The quality of oral intake was also unaffected by dexamethasone at 24 hr. Dexamethasone did produce a significant reduction in postdischarge vomiting, beyond the incidence found with ondansetron alone. RésuméObjectif La dexame´thasone diminue la morbiditeṕ ostope´ratoire apre`s une intervention chirurgicale pour ade´no-amygdalectomie, strabisme et extraction de la troisie`me molaire. Nous avons formule´l'hypothe`se que la dexame´thasone pouvait diminuer la douleur et d'autres morbidite´s chez des enfants subissant une chirurgie dentaire jusqu'a`24 heures apre`s l'intervention. Méthodes Une e´tude randomise´e, contrôle´e, a`triple insu a e´te´mene´e chez 200 enfants subissant une restauration

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“…Dans une étude récente, Numazaki et Fujii (2005) ont étudié l' effet des différentes doses de dexaméthasone et ont conclu que le meilleur effet face à une agression traumatique d' origine chirurgicale, était obtenu avec une dose de 8 mg. La dose de 16 mg n'apportait rien de plus sur le plan thérapeutique. Cette étude était faite chez les patients programmés pour une chirurgie buccale réalisée sous anesthésie générale [18].…”

Section: Voies D'administrationunclassified

Utilisation péri-opératoire des corticoïdes en chirurgie buccale

Benjelloun

Chami

Wady

2015

Actual. Odonto-Stomatol.

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RETRACTED: Reduction of postoperative emetic episodes and analgesic requirements with dexamethasone in patients scheduled for dental surgery

Cited by 30 publications

References 24 publications

Dexamethasone before total laparoscopic hysterectomy: a randomized controlled dose–response study

Dexamethasone before total laparoscopic hysterectomy: a randomized controlled dose–response study

Effect of dexamethasone on postoperative morbidity after dental rehabilitation in children

Utilisation péri-opératoire des corticoïdes en chirurgie buccale

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