RETRACTED: Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize

Abstract

The health effects of a Roundup-tolerant genetically modified maize (from 11% in the diet), cultivated with or without Roundup, and Roundup alone (from 0.1 ppb in water), were studied 2 years in rats. In females, all treated groups died 2-3 times more than controls, and more rapidly. This difference was visible in 3 male groups fed GMOs. All results were hormone and sex dependent, and the pathological profiles were comparable. Females developed large mammary tumors almost always more often than and before controls, the pituitary was the second most disabled organ; the sex hormonal balance was modified by GMO and Roundup treatments. In treated males, liver congestions and necrosis were 2.5-5.5 times higher. This pathology was confirmed by optic and transmission electron microscopy. Marked and severe kidney nephropathies were also generally 1.3-2.3 greater. Males presented 4 times more large palpable tumors than controls which occurred up to 600 days earlier. Biochemistry data confirmed very significant kidney chronic deficiencies; for all treatments and both sexes, 76% of the altered parameters were kidney related. These results can be explained by the non linear endocrine-disrupting effects of Roundup, but also by the overexpression of the transgene in the GMO and its metabolic consequences.

A four-generation feeding study with genetically modified (Bt) maize in laying hens

“…Nevertheless, there are critical comments about the duration of feeding studies (e.g., Séralini et al 2011Séralini et al , 2012. Although some of those studies and comments were not published in peer reviewed journals, they are nonetheless being considered in the public discussion (e.g., Velimirow et al 2008;Antoniou et al, 2012).…”

Why the postmodern attitude towards science should be denounced

“…Séralini [4], although highly controversial, might have paradoxically contributed to raising the awareness of the need for independent evaluations not linked to the GMO industry. One can only hope that such studies, if really set up, will clarify and pacify the field.…”

For a Holistic View of Biotechnology in West and Central Africa: What Can Integrated Development Approaches Contribute?

“…According to their studies, rats fed for two years with transgenic NK 603 corn and non-genetically engineered corn treated with Round Up died earlier than their fellow rats fed with untreated corn. The rats in the first two groups developed kidney, liver, and breast tumors, revealing the herbicide's long-term chronic toxicity [17]. However, Séralini's research has been criticized for a lack of scientific method and refuted by France's High Council of Biotechnologies [18] and the National Food Safety Agency [19].…”