RETRACTED: Effect of intersphincteric fistula tract ligation versus anal fistulectomy on pain scores and serum levels of vascular endothelial growth factor and interleukin-2 in patients with simple anal fistulas

Dong, Xin; Jia, Zhanbo; Yu, Bianfang; Zhang, Xuebin; Xu, Fagang; Tan, Liwen

doi:10.1177/0300060520949072

Cited by 10 publications

(6 citation statements)

References 27 publications

(40 reference statements)

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“…In the previous study the mean pain score on postoperative day 1 between LIFT (6.72 ± 0.53) versus Fistulectomy (7.01 ± 0.56) ( p < 0.05), on postoperative day 3 LIFT (5.66 ± 0.11) versus Fistulectomy (6.01 ± 0.11) ( p < 0.05) and on postoperative day 5 LIFT (2.43 ± 0.24) versus Fistulectomy (3.51 ± 0.25) ( p < 0.05). The results of this study were in concordant to our study [ 14 ]. b) Postoperative pus discharge and bleeding Postoperative pus discharge and bleeding was noted at various intervals postoperatively in our study.…”

Section: Discussionsupporting

confidence: 93%

The efficacy of Ksharsutra, Fistulectomy and Ligation of Intersphincteric Fistula Tract (LIFT) procedure in management of Fistula in ano a prospective observational study

Hariprasad

Kumar

et al. 2023

BMC Surg

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Background Fistula in ano is always a troublesome condition for the clinician and the patients owing to its complexity, recurrences, and high morbidity since ancient times. There is no gold standard treatment modality to date documented in the literature for complex fistula in ano. Material and methods We enrolled 60 consecutive adult patients attending the surgical outpatient department of a tertiary care centre in India, diagnosed with complex fistula in ano. Among them, 20 each in the Ligation of intersphincteric fistula tract (LIFT), Fistulectomy andKsharsutra(Special medicated seton) group were respectively recruited randomly. A prospective observational study was conducted. The primary outcomes were postoperative recurrence and morbidity. Post-operative morbidity is measured in terms of postoperative pain, postoperative bleeding, pus discharge and post-operative incontinence. The result of the study were analysed after 6 months of follow-up by clinical examination at outpatient department and at 18 months follow up done telephonically. Results At 6 months of follow-up, 2 patients (10%) had a recurrence in the Ligation of intersphincteric fistula tract procedure group, 3 patients (15%) in the fistulectomy group and 6 patients (30%) in Ksharsutra group, however 3(15%), 4(20%) and 9(45%) patients developed recurrence in Ligation of Intersphincteric fistula tract, Fistulectomy and Ksharsutra group respectively at 18 month of follow-up. The differences in the recurrence were not statistically significant.The mean Visual analogue score for postoperative pain after 24 h as well as after 48 h were statistically significant in Ligation of intersphincteric fistula tract versus Ksharsutra group (p < 0.05). The Visual analogue score for post–operative pain was also significant in the Ligation of the intersphincteric fistula tract versus the Fistulectomy group (p < 0.05). The patients treated via Fistulectomy and Ksharsutra had a higher proportion of bleeding (15%) as compared to the Ligation of intersphincteric fistula tract procedure. Postoperative morbidity was statistically significant between the Ligation of intersphincteric fistula tract versus the Ksharsutra and the Ligation of intersphincteric fistula tract versus Fistulectomy. Conclusion Ligation of intersphincteric fistula tract had less postoperative morbidity compared to Fistulectomy and Ksharsutra procedure; although recurrence was less compared to other methods it was statistically not significant.

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Section: Discussionsupporting

confidence: 93%

The efficacy of Ksharsutra, Fistulectomy and Ligation of Intersphincteric Fistula Tract (LIFT) procedure in management of Fistula in ano a prospective observational study

Hariprasad

Kumar

et al. 2023

BMC Surg

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“…All things considered, in our study, postoperative pain incidence in the case of LIFT (2.81) is far less than in the case of fistulectomy (5.64). A study conducted by Xin Dong showed similar results of less pain experienced by the LIFT group than fistulectomy (p<0.05) 18 . However, in that study postoperative pain was assessed on the 1st, 3rd, and 5th post-operative days while we assess the patients on the night of surgery when the effect of spinal anaesthesia may persist.…”

Section: Discussionmentioning

confidence: 74%

LIFT vs Fistulectomy: A Retrospective Cohort Study

Malik¹,

Nadeem²,

Aslam³

2022

PJMHS

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Background: Fistula-in-ano is defined as an epithelized abnormal tract connecting two surfaces; usually the rectal mucosa and perianal skin. The primary treatment for fistula is surgery for which many options are available. However, in this article, we will be discussing the comparison between LIFT and fistulectomy. Aim: To compare a conventional invasive technique of fistulectomy with a newly introduced minimally invasive LIFT procedure in terms of operative time, hospital stay, postoperative complications, and follow-up. Methods: A retrospective view of 135 patients was done who were operated on either by LIFT (n=59) (Group L) or fistulectomy (n=76) (Group F) over the period of three years and a comparison between two techniques was performed using Student’s t-test or Mann-Whitney test for continuous variables and Fisher’s exact test for categorical variables. Results: Our operative time for LIFT was greater than the fistulectomy. Post-operative pain was analyzed using the VAS pain scale, where Group L experienced less post-operative pain. Group F patients’ wounds took longer to heal as compared to Group L patients. Hence group L (LIFT) returned to work earlier. Post-operative complications such as wound discharge were reported more in Group F than in Group L. Same was observed in the case of post-operative infection rate. Two cases of wound granulation were observed in the case of LIFT (Group L) at one-month follow-up and one case of incontinence to flatus in the Group F group was documented at three-month follow-up in the patient's record. Thirty-seven patients’ complained of itching in Group F compared to 10 in Group L. Patients who had seton, complained of setons related problems. Conclusion: LIFT was a promising and sphincter-saving technique that was simple and easy to learn with faster healing rates and better patient contentment. Keywords: LIFT, fistulectomy, fistula-in-ano

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“…García-Botello et al found that the severity of urinary incontinence increased with the complexity of the fistula ( 35 ). Dong et al showed that damage to the postoperative sphincter can lead to anal incontinence ( 36 ). Moreover, postoperative healing time for anal fistulas and anorectal abscesses is also a long process, requiring at least 3 months to recover ( 37 ).…”

Section: Discussionmentioning

confidence: 99%

Restricted cubic spline model analysis of the association between anal fistula and anorectal abscess incidence and body mass index

Ye,

Huang,

Zheng

et al. 2024

Front. Surg.

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ObjectiveThe epidemiological profile of anal fistula and anorectal abscess has not been well studied. Based on the results of a retrospective cross-sectional survey, we aimed to investigate the potential influential factors associated with anal fistula and anorectal abscess.MethodsWe conducted a retrospective analysis of outpatients who visited the proctology department at China-Japan Friendship Hospital between January 2017 and May 2022. A comprehensive questionnaire was designed to collect potential influential factors, and according to formal anorectal examination and the corresponding diagnostic criteria, all the participants were divided into patients with anal fistula or perianal abscess and healthy control group. Multiple logistic regression was used to identify factors in significant association with anal fistula and perianal abscess. Additionally, we combined restricted cubic spline regression to examine the dose-response relationship between factors and the risk of developing anal fistula or anorectal abscess.ResultsThe present study included 1,223 participants, including 1,018 males and 206 females, with 275 anal fistulas, 184 anorectal abscesses, and 765 healthy controls. We found no statistically significant differences between patients and controls in basic information and preoperative assessment of life factors, except for body mass index. It was indicated that people with overweight or obesity were more prone to anal fistula (OR overweight = 1.35, 95% CI: 1.00–1.82, P = 0.047; OR obesity = 3.44, 95% CI: 2.26–5.26, P < 0.001) or anorectal abscess (OR overweight = 1.41, 95% CI: 1.00–1.99, P = 0.05; OR obesity: 2.24, 95% CI: 1.37–3.67, P = 0.001) than normal-weight individuals. The dose-response research indicated the J-shaped trend between the ascending BMI levels and the higher risk of suffering from anal fistula and anorectal abscess.ConclusionsOur findings indicate that overweight and obesity are risk factors for anal fistula and anorectal abscess, which plays a role in the prevention of anorectal diseases. This provides some theoretical basis for clinicians to provide health education to their patients.

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RETRACTED: Effect of intersphincteric fistula tract ligation versus anal fistulectomy on pain scores and serum levels of vascular endothelial growth factor and interleukin-2 in patients with simple anal fistulas

Cited by 10 publications

References 27 publications

The efficacy of Ksharsutra, Fistulectomy and Ligation of Intersphincteric Fistula Tract (LIFT) procedure in management of Fistula in ano a prospective observational study

The efficacy of Ksharsutra, Fistulectomy and Ligation of Intersphincteric Fistula Tract (LIFT) procedure in management of Fistula in ano a prospective observational study

LIFT vs Fistulectomy: A Retrospective Cohort Study

Restricted cubic spline model analysis of the association between anal fistula and anorectal abscess incidence and body mass index

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