Abstract:The damaged areas of brain tissues can be extracted by using segmentation methods, most of which are based on the integration of machine learning and data mining techniques. An important segmentation method is to utilize clustering techniques, especially the fuzzy C-means (FCM) clustering technique, which is sufficiently accurate and not overly sensitive to imaging noise. Therefore, the FCM technique is appropriate for multiple sclerosis diagnosis, although the optimal selection of cluster centers can affect s… Show more
“…Iswisi et al [ 47 ] developed a ML model for MS diagnosis based on the Harris Hawks optimization (HHO) algorithm using MRI scans of 10 patients. The fuzzy C-means (FCM) algorithm was combined with the HHO algorithm for the extraction of lesions and reduction of the segmentation error.…”
Multiple Sclerosis (MS) is a disease that impacts the central nervous system (CNS), which can lead to brain, spinal cord, and optic nerve problems. A total of 2.8 million are estimated to suffer from MS. Globally, a new case of MS is reported every five minutes. In this review, we discuss the proposed approaches to diagnosing MS using machine learning (ML) published between 2011 and 2022. Numerous models have been developed using different types of data, including magnetic resonance imaging (MRI) and clinical data. We identified the methods that achieved the best results in diagnosing MS. The most implemented approaches are SVM, RF, and CNN. Moreover, we discussed the challenges and opportunities in MS diagnosis to improve AI systems to enable researchers and practitioners to enhance their approaches and improve the automated diagnosis of MS. The challenges faced by automated MS diagnosis include difficulty distinguishing the disease from other diseases showing similar symptoms, protecting the confidentiality of the patients’ data, achieving reliable ML models that are also easily understood by non-experts, and the difficulty of collecting a large reliable dataset. Moreover, we discussed several opportunities in the field such as the implementation of secure platforms, employing better AI solutions, developing better disease prognosis systems, combining more than one data type for better MS prediction and using OCT data for diagnosis, utilizing larger, multi-center datasets to improve the reliability of the developed models, and commercialization.
“…Iswisi et al [ 47 ] developed a ML model for MS diagnosis based on the Harris Hawks optimization (HHO) algorithm using MRI scans of 10 patients. The fuzzy C-means (FCM) algorithm was combined with the HHO algorithm for the extraction of lesions and reduction of the segmentation error.…”
Multiple Sclerosis (MS) is a disease that impacts the central nervous system (CNS), which can lead to brain, spinal cord, and optic nerve problems. A total of 2.8 million are estimated to suffer from MS. Globally, a new case of MS is reported every five minutes. In this review, we discuss the proposed approaches to diagnosing MS using machine learning (ML) published between 2011 and 2022. Numerous models have been developed using different types of data, including magnetic resonance imaging (MRI) and clinical data. We identified the methods that achieved the best results in diagnosing MS. The most implemented approaches are SVM, RF, and CNN. Moreover, we discussed the challenges and opportunities in MS diagnosis to improve AI systems to enable researchers and practitioners to enhance their approaches and improve the automated diagnosis of MS. The challenges faced by automated MS diagnosis include difficulty distinguishing the disease from other diseases showing similar symptoms, protecting the confidentiality of the patients’ data, achieving reliable ML models that are also easily understood by non-experts, and the difficulty of collecting a large reliable dataset. Moreover, we discussed several opportunities in the field such as the implementation of secure platforms, employing better AI solutions, developing better disease prognosis systems, combining more than one data type for better MS prediction and using OCT data for diagnosis, utilizing larger, multi-center datasets to improve the reliability of the developed models, and commercialization.
“…e early stages of the disease have no symptoms so that it can be easily diagnosed. Due to the annoyance of this disease and the similarity of cardiac arrhythmia symptoms to other heart diseases, designing an intelligent system to diagnose this disease seems necessary [2][3][4][5][6][7][8][9][10][11].…”
Automatic diagnosis of arrhythmia by electrocardiogram has a significant role to play in preventing and detecting cardiovascular disease at an early stage. In this study, a deep neural network model based on Harris hawks optimization is presented to arrive at a temporal and spatial fusion of information from ECG signals. Compared with the initial model of the multichannel deep neural network mechanism, the proposed model of this research has a flexible input length; the number of parameters is halved and it has a more than 50% reduction in computations in real-time processing. The results of the simulation demonstrate that the approach proposed in this research had a rate of 96.04%, 93.94%, and 95.00% for sensitivity, specificity, and accuracy. Furthermore, the proposed approach has a practical advantage over other similar previous methods.
“…A biogeography‐based optimization method was proposed to address the FCM clustering algorithm issue and determine the initial cluster centers. This method combines the artificial bee colony (ABC) and PSO algorithm with the FCM segmentation technique, providing a solution for the initial clustering problem and outperforming the standard FCM clustering algorithm in terms of performance 21–24 . A krill herd optimization (KHO) algorithm was proposed for image segmentation based on multilevel thresholding, maximizing Kapur's or Otsu's objective function to determine the cutoff value and significantly reducing processing time compared to other methods 25,26 .…”
White matter pathologies analysis is important for segmenting multiple sclerosis (MS) lesions in MRI slices. Myelin damage affects motor function, sensory conflicts, paralysis, and vision. Extracting an optimistic number of hidden characteristic features induces high feature maps and reduces redundancy and dimensionality. A framework based on Hybrid Deep Convolutional Neural Networks (HD‐CNN) is presented to classify MS based on the acquired optimistic feature characteristic. First, Chaotic Leader‐Selective Particle Swarm Optimization uses the pixel intensity ratio of the targeted region to extract the most hidden white matter features. Second, Refined Slime Mold categorizes hidden features and ensures that the necessary features are selected effectively for a better segmentation result. An effective inbuilt Maximum Bidirectional Gradient Classifier accurately classifies MS lesions by detecting white matter spots in the target region. Finally, we will evaluate the proposed HD‐CNN framework using the industry‐standard University Medical Centre Ljubljana (UMCL) and international symposium on biomedical imaging (ISBI) 2015 datasets as benchmarks. It reaches 98.56%, 93.15%, and 98.44% accuracy for FLAIR, T1W, and T2W, respectively. Our HD‐CNN improves MS classification over other state‐of‐the‐art techniques, compared with accuracy, F‐score, Recall, Precision, Dice, and Jaccard indexes values.
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