RETRACTED ARTICLE: The teratogenic effect of pregabalin on heart, liver and kidney in rats: a light microscopic, electron microscopic and immunohistochemical study

Ismail, Omnia I.; Shaltout, Eman; Abdellah, Nora; Hetta, Diab Fuad; El-Ghani, Wael M. A. Abd; Abdelzaher, Lobna A.; Mahmoud, Ahmed Mohamed Mohamed; Hasan, Asmaa M; Rashed, Noha A.; Ebrahem, Noha

doi:10.1186/s40360-021-00546-2

Cited by 3 publications

(1 citation statement)

References 47 publications

(46 reference statements)

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“…In recent years, there have been advancements in the field of seizure prediction, and that has allowed intervention during seizures, such as medications or invasive electrodes [3][4][5]. The drawbacks of such methods include the harmful effects of epileptic drugs on the liver and kidneys [6]; as well as adverse effects on female reproductive organs [7], also using invasive electrodes causes irreversible damage to brain tissues.…”

Section: Introductionmentioning

confidence: 99%

General and patient-specific seizure classification using deep neural networks

Massoud

Abdelzaher

Kuhlmann

et al. 2023

Analog Integr Circ Sig Process

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Seizure prediction algorithms have been central in the field of data analysis for the improvement of epileptic patients’ lives. The most recent advancements of which include the use of deep neural networks to present an optimized, accurate seizure prediction system. This work puts forth deep learning methods to automate the process of epileptic seizure detection with electroencephalogram (EEG) signals as input; both a patient-specific and general approach are followed. EEG signals are time structure series motivating the use of sequence algorithms such as temporal convolutional neural networks (TCNNs), and long short-term memory networks. We then compare this methodology to other prior pre-implemented structures, including our previous work for seizure prediction using machine learning approaches support vector machine and random under-sampling boost. Moreover, patient-specific and general seizure prediction approaches are used to evaluate the performance of the best algorithms. Area under curve (AUC) is used to select the best performing algorithm to account for the imbalanced dataset. The presented TCNN model showed the best patient-specific results than that of the general approach with, AUC of 0.73, while ML model had the best results for general classification with AUC of 0.75.

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