RETRACTED ARTICLE: Does immediate postpartum curettage of the endometrium accelerate recovery from preeclampsia–eclampsia? A randomized controlled trial

Goda, Hosam; Raghib, Muhammad Faraz; Barakat, Rafik; Elsamanoudy, Ayman Z; Badawy, Ahmed

doi:10.1007/s00404-013-2866-0

Cited by 13 publications

(9 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, both studies did suggest a reduction in the absolute number of eclamptic seizures in the curettage group compared with no intervention. 15 58 In one, however, there was a relevant difference between the study groups; 28/28 (100%) in the control group were eclamptic at enrolment, compared with 9/20 (45%) in the intervention group. 58 Four studies reported safety data, with none reporting any complications related to the intervention ( table 2B ).…”

Section: Resultsmentioning

confidence: 93%

“…Of the 39 studies, 9 (23%) included ≥100 participants, and only 2 studies included ≥200 participants. 15 16 Four were from lower middle-income settings 15 17–19 (classified according to the United Nations 20 ), and 13/39 (33%) studies had follow-up periods longer than 7 days (online supplementary appendix S4 ). Only 5/39 (13%) and 7/39 (18%) studies, respectively, reported maternal mortality or major maternal morbidity, and while the majority of studies did report some measure of BP control, three did not ( table 2A,B ).…”

Section: Resultsmentioning

confidence: 99%

“…57 Only one study reported maternal mortality, and there was no difference between groups. 15 Two reported major maternal morbidity, but neither performed any statistical analysis ( table 2B ). However, both studies did suggest a reduction in the absolute number of eclamptic seizures in the curettage group compared with no intervention.…”

Section: Resultsmentioning

confidence: 99%

“…All eight studies compared curettage with standard care (ie, no additional intervention), and all suggested that uterine curettage resulted in a significantly lower BP. 15 18 57–62 One of these had two control groups: standard care and oral nifedipine; when compared with oral nifedipine, no difference was noted with curettage. 60 …”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Postpartum management of hypertensive disorders of pregnancy: a systematic review

et al. 2017

View full text Add to dashboard Cite

ObjectivesHypertensive disorders of pregnancy (HDP) affect one in ten pregnancies and often persist postpartum when complications can occur. We aimed to determine the effectiveness and safety of pharmacological interventions, other interventions and different care models for postpartum hypertension management.DesignA systematic review was undertaken. Nine electronic databases, including Medline, were searched from inception to 16 March 2017. After duplicate removal, 4561 records were screened. Two authors independently selected studies, extracted study characteristics and data, and assessed methodological quality.SettingRandomised controlled trials, case–control studies and cohort studies from any country and healthcare setting.ParticipantsPostnatal women with HDP.InterventionsTherapeutic intervention for management of hypertension, compared with another intervention, placebo or no intervention.Primary and secondary outcome measuresOutcome data were collected for maternal mortality and severe morbidity; systolic, diastolic and mean arterial blood pressure (BP) control; and safety data. Secondary outcome data collected included the length of postnatal hospital stay and laboratory values.Results39 studies were included (n=2901). Results were heterogeneous in terms of intervention, comparison and outcome requiring a narrative approach. There were insufficient data to recommend any single pharmacological intervention. 18 studies reported calcium-channel blockers, vasodilators and beta-blockers lowered BP postpartum. 12 of these reported safety data. Limited data existed regarding management in the weeks following hospital discharge. Neither loop diuretics (three studies) nor corticosteroids (one study) produced clinical benefit. Uterine curettage significantly reduced BP over the first 48 hours postpartum (range 6–13 mm Hg) compared with standard care (eight studies), with safety data only reported by four of eight studies.ConclusionThere was insufficient evidence to recommend a particular BP threshold, agent or model of care, but three classes of antihypertensive appeared variably effective. Further comparative research, including robust safety data, is required. Curettage reduced BP, but without adequate reporting of harms, so it cannot currently be recommended.

show abstract

Section: Resultsmentioning

confidence: 93%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Postpartum management of hypertensive disorders of pregnancy: a systematic review

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Two independent reviewers evaluated 162 potentially relevant studies. Seventy‐nine randomised trials reporting data from 31 615 maternal and 28 172 of their offspring met our inclusion criteria (Figure ) . Included trials evaluated 55 different interventions, of which 29 (37%) evaluated antihypertensive medication and 21 (27%) anticonvulsant medication (Table S1).…”

Section: Resultsmentioning

confidence: 99%

Outcome reporting across randomised controlled trials evaluating therapeutic interventions for pre‐eclampsia

Duffy

Hirsch²,

Kawsar

et al. 2017

BJOG

View full text Add to dashboard Cite

Background Standardising outcome collection and reporting in pre‐eclampsia trials requires an appraisal of current outcome reporting. Objectives To map maternal and offspring outcome reporting across randomised trials evaluating therapeutic interventions for pre‐eclampsia. Search strategy Randomised trials were identified by searching bibliographical databases from inception to January 2016. Selection criteria Randomised controlled trials. Data collection and analysis We systematically extracted and categorised outcome reporting. Main results Seventy‐nine randomised trials, reporting data from 31 615 maternal participants and 28 172 of their offspring, were included. Fifty‐five different interventions were evaluated. Included trials reported 119 different outcomes, including 72 maternal outcomes and 47 offspring outcomes. Maternal outcomes were inconsistently reported across included trials; for example, 11 trials (14%) reported maternal mortality, reporting data from 12 422 participants, and 16 trials (20%) reported cardiovascular morbidity, reporting data from 14 963 maternal participants. Forty‐three trials (54%) reported fetal outcomes and 23 trials (29%) reported neonatal outcomes. Twenty‐eight trials (35%) reported offspring mortality. There was poor reporting of childhood outcomes: six trials (8%) reported neurodevelopmental outcomes. Less than half of included trials reported any relevant information regarding harms for maternal participants and their offspring. Conclusions Most randomised trials evaluating interventions for pre‐eclampsia are missing information on clinically important outcomes, and in particular have neglected to evaluate efficacy and safety in the offspring of participants. Developing and implementing a minimum data set, known as a core outcome set, in future pre‐eclampsia trials could help to address these issues. Tweetable abstract Future #preeclampsia research requires a core outcome set to reduce #research waste. https://twitter.com/coreoutcomes https://twitter.com/jamesmnduffy International Prospective Register of Systematic Reviews: CRD42015015529; http://www.crd.york.ac.uk/PROSPERO/display_record.aspID=CRD42015015529.

show abstract

Pilot study: placental biomarker predictive capability (sFlt-1, PlGF and their ratio) of postpartum maternal outcome

Hamza

Gerlinger

Radosa

et al. 2019

Arch Gynecol Obstet

View full text Add to dashboard Cite

RETRACTED ARTICLE: Does immediate postpartum curettage of the endometrium accelerate recovery from preeclampsia–eclampsia? A randomized controlled trial

Abstract: Immediate postpartum curettage is a safe and effective procedure and can accelerate recovery from pre-eclampsia or eclampsia.

Cited by 13 publications

References 14 publications

Postpartum management of hypertensive disorders of pregnancy: a systematic review

Postpartum management of hypertensive disorders of pregnancy: a systematic review

Outcome reporting across randomised controlled trials evaluating therapeutic interventions for pre‐eclampsia

Pilot study: placental biomarker predictive capability (sFlt-1, PlGF and their ratio) of postpartum maternal outcome

Contact Info

Product

Resources

About