RETRACTED ARTICLE: CT, MRI, and 18F-FDG PET/CT imaging features of seven cases of adult pancreatoblastoma

Abstract

Objective This study mainly analysed the imaging data for seven cases of adult pancreatoblastoma (PB) and summarized additional imaging features of this disease based on a literature review, aiming to improve the understanding and diagnosis rate of this disease. Materials and methods The imaging data for seven adult patients pathologically diagnosed with adult PB were retrospectively analysed. Among the seven patients, six underwent computed tomography (CT) scans, two patients underwent abdominal magnetic resonance imaging (MRI), and five patients underwent 18F-FDG PET/CT. Results The tumours were located in the head of the pancreas in three cases, in the tail of the pancreas in two cases, and in the gastric antrum and neck of the pancreas in one case. Six tumours showed blurred edges, and an incomplete envelope was observed in only two cases when enhanced, which showed extruded growth and cyst-solid masses; one tumour was a solid mass with ossification. Showing mild or significant enhancement in the arterial phase (AP) for six cases. In the MRI sequence, isointensity was found on suppressed T1-weighted imaging, and hyperintensity was noted on suppressed T2-weighted imaging in two cases, with significant enhancement. Pancreatic duct dilatation was found in four cases. Tumour 18F-FDG PET/CT imaging exhibited high uptake in five cases. Conclusion Adult PB involves a single tumour and commonly manifests as cystic-solid masses with blurred edges. Capsules are rare, ossification is an important feature, tumours can also present in ectopic pancreatic tissues, with mild or strengthening in the AP, and 18F-FDG uptake is high. These features are relatively specific characteristics in adult PB.

Blastomas of the digestive system in adults: A review

“…Pancreatoblastomas are single, large, well-delineated, circular or lobulated masses with scattered or aggregate calcifications visible on both CT and MRI. Heterogeneous character may reflect a cystic component of some tumors[ 34 ]. Contrast imaging shows enhancement in the arterial phase that can mimic a hypervascular neuroendocrine tumor[ 34 - 36 ].…”

“…Heterogeneous character may reflect a cystic component of some tumors[ 34 ]. Contrast imaging shows enhancement in the arterial phase that can mimic a hypervascular neuroendocrine tumor[ 34 - 36 ]. Common bile duct involvement ( i.e.…”

“…Common bile duct involvement ( i.e. , dilatation) is apparent in some pancreatic head tumors[ 34 , 35 , 37 , 38 ]. Serum AFP has been noted to be increased in 68% cases[ 18 , 39 ] and may be used to monitor the effectiveness of therapy[ 40 ].…”