Retracing the horizontal transfer of a novel innate immune factor inDrosophila
Rebecca L. Tarnopol,
Josephine Tamsil,
Gyöngyi Cinege
et al.
Abstract:SummaryImmune systems are among the most dynamically evolving traits across the tree of life, and long-lived macroparasites play an outsized role in shaping animal immunity. Even without adaptive immunity, insects have evolved potent innate immune strategies to neutralize such enemies, including nematodes and parasitoid wasps. One such strategy relies on endosymbioses between insects and toxin-expressing bacteria. Here, we use genome editing inDrosophila melanogasterto retrace the evolution of two of such toxi… Show more
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