Rétinopathie pigmentaire et hyalopathie astéroïde

Wafi, Mariam El; Raïs, L.; Lahbil, D.; Hamdani, M.; Rachid, R.; Belhadji, M. El; Laouissi, N.; Zaghloul, K.; Amraoui, A.

doi:10.1016/s0181-5512(04)96217-1

Cited by 3 publications

(3 citation statements)

References 10 publications

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“…Tel est le cas avec notre observation où la hyalopathie astéroïde est présente chez un diabétique. Par contre Fawzi dans une étude rétrospective réalisée à l'université de Californie à Los Angeles a montré qu'il n'y avait pas de corrélation statistiquement significative entre hyalopathie astéroïde et diabète sucré [5, 6]. Certains auteurs ont signalé la présence de la hyalopatie astéroïde dans les deux yeux et ont conclu que le sexe masculin était le plus atteint [6, 7].…”

Section: Discussionunclassified

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Hyalopathie asteroide: à propos d’une observation

Bienvenu¹,

Angel²,

Leon³

et al. 2017

Pan Afr Med J

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Section: Discussionunclassified

“…La hyalopathie astéroïde est une pathologie dégénérative rare du vitré [1]. Sa prévalence est estimée entre 0,15 et 0,9% dans la population [2].…”

Section: Introductionunclassified

Hyalopathie asteroide: à propos d’une observation

Bienvenu¹,

Angel²,

Leon³

et al. 2017

Pan Afr Med J

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“…58 Active lipid metabolism has also been reported to occur in the vitreous from Irish setters with hereditary rod-cone dysplasia (RCD). 52 AH has also been documented to be present in patients with retinitis pigmentosa, [59][60][61] or pigmentary retinal degeneration. 62 In addition to retinal changes, other factors appear to influence the development of AH in dogs.…”

Section: The Galactose-fed Dogmentioning

confidence: 99%

Asteroid hyalosis: pathogenesis and prospects for prevention

Kador

Wyman

2008

Eye

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Asteroid hyalosis (AH) is a common degenerative process in which fatty calcium globules collect within the vitreous humour. The condition rarely causes visual disturbances, and surgical removal is only rarely required. The presence of AH has been associated with systemic diseases such as diabetes; however, research in this area has been hampered by the lack of an animal model of AH. Recently, we have reported that AH occurs in galactose-fed beagles that develop the advanced stages of diabetes-like retinopathy. Comparisons of vitreous humour containing asteroid bodies (ABs) collected from these galactose-fed beagles and vitreous samples from age-matched normal beagles without ABs indicate that ABs contain calcium and phosphorous. Subtraction analysis of chloroform extracts of the vitreous samples by electrospray mass spectroscopy resulted in the identification of the quasimolecular ion of 1,2-dipalmitoyl-glycero-3-phosphoethanolamine (DPPE) as the main component of ABs. Since several reports indicate that ABs are composed of lipid-calcium complexes, we have proposed that the main component of ABs in the galactose-fed dogs with AH is a quasimolecular ion of DPPE in which two molecules of DPPE are complexed through their phosphates groups with calcium. We suggest that these lipid components diffuse into the vitreous from the degenerating retinas of these dogs.

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Spieler

Rössle²

2012

Essentials of Diagnostic Pathology

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Rétinopathie pigmentaire et hyalopathie astéroïde

Cited by 3 publications

References 10 publications

Hyalopathie asteroide: à propos d’une observation

Hyalopathie asteroide: à propos d’une observation

Asteroid hyalosis: pathogenesis and prospects for prevention

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