Abstract:We determined retinoids liver content in male and female mice fetuses to study a possible sex difference during prenatal development, and to ascertain if vitamin A metabolism is similar in both sexes. The study was performed between developmental days E15-E19, and the fetuses were collected from two main groups: control (no manipulation) and vitamin A (administration of vitamin A on developmental day E14). Each group was subdivided by sex and retinoids were analyzed by high performance liquid chromatography (H… Show more
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