Retinoids, Epigenetic Changes during Stem Cell Differentiation, and Cell Lineage Choice

Gudas, Lorraine J.

doi:10.1002/9781118628003.ch12

Cited by 1 publication

(1 citation statement)

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“…According to Gudas (1992), RA (vitamin A) is involved in the regulation of the differentiation of several types of cells, acting as a signalling molecule for gene expression, influencing the expression of genes responsible for encoding glycoproteins, proteases (collagenase), proteins such as keratins, and for different growth factors.…”

Section: Discussionmentioning

confidence: 99%

Performance and bone characteristics of broilers fed diets supplemented with vitamin A at different concentrations

Savaris,

Pozza,

Polese

et al. 2023

Animal Physiology Nutrition

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This work evaluated the influence of vitamin A on performance, organ weight, and bone and skin characteristics in broilers (Cobb 500) at 21 and 42 days of age. A total of 1920 chickens were distributed in a randomised design, considering six vitamin A supplementation levels (0, 6000, 16,000, 26,000, 36,000, and 46,000 IU kg−1), with 16 replicates and 20 chickens per experimental unit, established due to rising the range of vitamin levels observed in the literature to evaluate the effect of vitamin A on broilers. At 22 days, half of the replicates from each treatment continued receiving the initial diet, and the other eight repetitions received diets without vitamin A (0 IU kg−1) until 42 days. The level of vitamin A influenced feed intake (FI) and body weight gain (BWG) until 21 days for all treatments. Broilers at 21 days of age had a more significant BWG at a vitamin A supplementation level of 28,209 IU kg−1. At 42 days, vitamin A influenced the BWG and FI of broilers at treatments that were not supplemented after 21 days. Treatments supplemented up to 42 days showed quadratic responses to vitamin A for BWG, FI, and feed conversion. The vitamin A levels influenced the relative weights of the small intestine, pancreas, gizzard, abdominal fat, Seedor index, and breaking strength at 42 days, where the adequate supplementation of vitamin A improved these characteristics in broilers. Vitamin A supplementation from 22 to 42 days old did not affect broiler performance. An increased BWG was obtained when vitamin A supplementation occurred until 42 days, with supplementation of 29,375 IU kg−1 and a lower response of feed conversion with the addition of 27,775 IU kg−1.

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Section: Discussionmentioning

confidence: 99%