European Handbook of Dermatological Treatments 2015
DOI: 10.1007/978-3-662-45139-7_147
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Retinoids

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Cited by 2 publications
(1 citation statement)
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“…The concept of cumulative dose (mg/kg bodyweight), introduced by Harms in 1989, is the total amount of oral isotretinoin taken by the patient over the entire duration, divided by the bodyweight 31,32 . According to the EMA, a treatment course of 16–24 weeks is normally sufficient to achieve remission and it is mentioned that no substantial additional benefit is to be expected beyond a cumulative treatment dose of 120–150 mg/kg 2…”
Section: Clinical Question 4: Is a Cumulative Dose Necessary?mentioning
confidence: 99%
“…The concept of cumulative dose (mg/kg bodyweight), introduced by Harms in 1989, is the total amount of oral isotretinoin taken by the patient over the entire duration, divided by the bodyweight 31,32 . According to the EMA, a treatment course of 16–24 weeks is normally sufficient to achieve remission and it is mentioned that no substantial additional benefit is to be expected beyond a cumulative treatment dose of 120–150 mg/kg 2…”
Section: Clinical Question 4: Is a Cumulative Dose Necessary?mentioning
confidence: 99%