Retinoic acid induced specific changes in the phosphoproteome of C17.2 neural stem cells
Cheng Zhang,
Lite Ge,
Huali Xie
et al.
Abstract:Retinoic acid (RA), a vitamin A derivative, is an effective cell differentiating factor which plays critical roles in neuronal differentiation induction and the production of neurotransmitters in neurons. However, the specific changes in phosphorylation levels and downstream signalling pathways associated with RA remain unclear. This study employed qualitative and quantitative phosphoproteomics approaches based on mass spectrometry to investigate the phosphorylation changes induced by RA in C17.2 neural stem c… Show more
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