Retinoblastoma in a 12 year old girl: a case report

Odogu,; Udoye, Ezenwa Patrick; Azonobi, IR

doi:10.5958/j.2319-5886.3.2.089

Cited by 3 publications

(4 citation statements)

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“…10 Although late presenting retinoblastoma is uncommon, there are a number of case reports of these cases. 10,11,12,13 A similar case of late presentation of retinoblastoma in a teen with Aicardi Syndrome has been reported from Houston. 14 There are a number of explanations for the late presentation of retinoblastomas.…”

Section: Figure 1: Leucocoria In the Left Eyementioning

confidence: 60%

Unilateral Sporadic Retinoblastoma in an 11-Year-Old Child: A Rare Case Report

Jha¹,

Govindaraj²,

Dora³

et al. 2016

jebmh

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BACKGROUNDRetinoblastoma is the commonest intraocular tumour of childhood. Majority of cases are diagnosed before 5 years of age, with late presentation being a rarity. CASE REPORTAn 11-year-old boy presented to our OPD with diminution of vision and white pupillary reflex in the left eye since 1 month. Right eye was normal. Fundus examination of left eye revealed a mass in the inferior quadrant with vitreous haemorrhage. Bscan and MRI were suggestive of retinoblastoma and showed no signs of optic nerve involvement. Subsequently, the patient underwent enucleation of left eye. Primary orbital implant was given. Diagnosis was confirmed histopathologically. CONCLUSIONLate presentation of retinoblastoma though uncommon can cause acute visual impairment. Retinoblastoma should be considered in the differential diagnosis of leukocoria in any age group. HOW TO CITE THIS ARTICLE:Jha N, Govindaraj B, Dora J, et al. Unilateral sporadic retinoblastoma in an 11-year-old child: A rare case report.

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Section: Figure 1: Leucocoria In the Left Eyementioning

confidence: 60%

Unilateral Sporadic Retinoblastoma in an 11-Year-Old Child: A Rare Case Report

Jha¹,

Govindaraj²,

Dora³

et al. 2016

jebmh

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“…Karciogluetal found both clinical and histopathologic features were atypical in older children which showed Flexner winter Steiner differentiation albeit fewer than would in younger patients. 13…”

Section: Clinical Mri and Histological Pictures Of The Eye Ballmentioning

confidence: 99%

Retinoblastoma – Typical and atypical clinical manifestations presented at tertiary eye care centre

Sultana¹,

Mallapragada

2022

IJCEO

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: Purpose is to study the various typical and atypical manifestations of the retinoblastoma presented to our department.: Prospective study.: 2 years, January 2020 to December 2021.: All children presented with various signs and symptoms and cases with tumour suspicious manifestations were evaluated. Detailed birth history from parents, slit lamp examination, indirect ophthalmoscopy, B Scan, CT Scan Orbit (plain and contrast), MRI Orbit (plain and contrast) when tumour extension was suspected and documentation done in all cases.: Atypical manifestations requires proper evaluation to exclude Pseudo retinoblastomas. Many clinical conditions will masquerade the tumour and cause confusion in diagnosis. Pseudo retinoblastomas which reported in our study were commonly PHPV and Coats disease. One case of Retinoblastoma was also presented like Ocular cysticercosis with inflammatory signs in anterior and posterior segment, oral steroids were given, vitreous seeds which were present in anterior chamber disappeared after steroids and fundus showed creamish white lesion filling the entire vitreous cavity. Masquerades will cause delay in the diagnosis, which can lead to extension of tumour.: Diagnosis is not easy, most of the times in children particularly when media is not clear, delay in diagnosis may require enucleation where globe salvage may not be possible, sometimes intracranial extension of the tumour will increase the mortality.

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“…Retinoblastoma is the most common primary malignant intraocular tumor in children that develops from the immature cells of the retina which are the light-detecting cells of the eye. Children with retinoblastoma have a hereditary genetic defect associated with retinoblastoma, in other cases it is caused by a congenital mutation in the chromosome 13 gene, 13q14 [1]. It is almost exclusively found in young children with mean age of 5 years.…”

Section: Introductionmentioning

confidence: 99%

“…These tumors are characterized both cytologically and histologically by a predominantly small round to oval and relatively undifferentiated cells. The disparity in treatment modalities and clinical outcome in the different subsets of SBRCTs makes the correct diagnosis crucial [1,2]. Retinoblastoma is the most common primary malignant intraocular tumor in children that develops from the immature cells of the retina which are the light-detecting cells of the eye.…”

Section: Introductionmentioning

confidence: 99%

Ocular retinoblastoma and neuroblastoma: A cytological impression

Akhtar¹,

Juneja²,

Haiyat³

et al. 2018

Journal of Surgery and Medicine

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Small-round-blue-cell tumor (SRBCT) or a small-round-cell tumor (SRCT) is a group of malignant neoplasms which are seen more often in children (0-20 years-old) than in adults. They generally include Ewing's sarcoma, peripheral neuroectodermal tumor (PNET), rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma, retinoblastoma, neuroblastoma, hepatoblastoma, and nephroblastoma or Wilms' tumor as differential diagnoses of small round cell tumors. They have a characteristic appearance consisting of small round cells that stain blue on Hematoxylin and Eosin stained sections. They typically represent undifferentiated cells which are composed of primitive cells with minimal or no differentiation. Accurate diagnosis of these cancers is essential because the treatment options, responses to therapy and prognoses vary widely depending on the diagnosis. A multimodal approach is employed with fine needle aspiration cytology (FNAC) as an important modality of diagnosis for these tumors. We will discuss ocular retinoblastoma and neuroblastoma in our case series which were diagnosed on fine needle aspiration itself and were later confirmed on histopathological examination. This study was also undertaken to determine the utility and safety of intraocular FNAC as a supportive diagnostic tool where clinical features and imaging were found to be inconclusive.

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Retinoblastoma in a 12 year old girl: a case report

Cited by 3 publications

References 0 publications

Unilateral Sporadic Retinoblastoma in an 11-Year-Old Child: A Rare Case Report

Unilateral Sporadic Retinoblastoma in an 11-Year-Old Child: A Rare Case Report

Retinoblastoma – Typical and atypical clinical manifestations presented at tertiary eye care centre

Ocular retinoblastoma and neuroblastoma: A cytological impression

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