Retinal vessel oxygen saturation and vessel diameter in retinitis pigmentosa at various ages

Abstract

The shifting characteristics of retinal vessel oxygen saturation suggest that the pathological mechanism of retinal oxygen metabolic disorder differs by age in patients with RP.

Lack of differences in the regional variation of oxygen saturation in larger retinal vessels in diabetic maculopathy and proliferative diabetic retinopathy

“…However, the fact that there was no significant difference between the peripapillary oxygen saturation in the UT vessels in the disc centred image and the saturation proximally from branches on the same vessels in images centred on the vascular arcades supports that illumination had not been a biasing factor for the calculation of saturation values. It has been shown that the calculation of saturation becomes unpredictable in thin and short vessel segments,20 and therefore, only vessels with a diameter larger than six pixels, with a diameter of at least 50% of their parent vessel, and vessel segments longer than 50 pixels were considered 13. It is unlikely that the conclusions of the study had been influenced by the selection of fundus images with this specific branching pattern.…”

Reduced metabolic function and structural alterations in inherited retinal dystrophies: investigating the effect of peripapillary vessel oxygen saturation and vascular diameter on the retinal nerve fibre layer thickness

“…; Zong et al. ). Within the RP group, strong correlations between the retinal metabolic demand and the structural (Türksever et al.…”

Hyperspectral Image Mapping Spectrometry for Retinal Oximetry Measurements in Four Diseased Eyes

“…Several studies have found reduced oxygen saturation values in occluded arteries and veins [14–17] and increased venous oxygen saturation in patients with exudative age-related macular degeneration (AMD) [18], advanced primary open-angle glaucoma [19–21], diabetic retinopathy[22–24], and retinitis pigmentosa [25, 26]. For patients with retinitis pigmentosa, increased arterial oxygenation saturation and increased arteriovenous oxygen saturation differences have been observed, with age seemingly affecting these values [27, 28]. Another study on primary open-angle glaucoma [29] indicated no change in venous oxygen saturation.…”