Retinal Vein Occlusion and Traditional Risk Factors for Atherosclerosis

Abstract

To determine whether retinal vein occlusion (RVO) is related to systemic hypertension, diabetes mellitus, and hyperlipidemia. Methods:We systematically retrieved all studies published between January 1985 and July 2007 that compared cases with any form of RVO, including central and branch RVO, with controls. We generated pooled odds ratios (ORs) and estimates of the populationattributable risk percentages for systemic hypertension, diabetes mellitus, and hyperlipidemia.

Cataract Surgery Is Not Associated with Decreased Risk of Retinal Vein Occlusion

“… 40 A similar trend of finding associations between DR and CRVO, but not with BRVO, were seen in meta-analyses. 41 , 42 In addition to the differences in the distribution of DR, another possible explanation for the discrepancy between our study results and previously published results is that we relied on DR codes rather than systemic diabetes mellitus codes. Thus, we would have considered only cases of diabetes severe enough to be accompanied by ocular manifestations, unlike previous studies.…”

Cataract Surgery Is Not Associated with Decreased Risk of Retinal Vein Occlusion

“… 40 A similar trend of finding associations between DR and CRVO, but not with BRVO, were seen in meta-analyses. 41 , 42 In addition to the differences in the distribution of DR, another possible explanation for the discrepancy between our study results and previously published results is that we relied on DR codes rather than systemic diabetes mellitus codes. Thus, we would have considered only cases of diabetes severe enough to be accompanied by ocular manifestations, unlike previous studies.…”

Characteristics of Hematologic Parameters in Young Patients with Retinal Vein Occlusion

“…In this study, the prevalence of hyperlipidemia, hypertension, and diabetes mellitus in patients with RVO was 53.1%, 31.3%, and 9.4%, respectively. These results are consistent with previous studies, which indicated that RVO in young people is usually accompanied by systemic diseases [ 5 , 20 , 21 ]. Thus, comprehensive screening for systemic and hematologic factors is an important part of the initial workup of young patients with RVO.…”

Role of Advanced Glycation End Products in Assessment of Diabetes Mellitus as a Risk Factor for Retinal Vein Occlusion

“…HTN was the most common risk factor in both groups of RVO, although HTN was significantly more frequent in the BRVO group (in 81.8% in BRVO compared to 58.3% in CRVO group). These findings agreed with data from other authors [14,38,45]. Similar to data from the literature, in this study, hyperlipidemia was noted in approximately 20% of RVO cases (16.7% and 27.3% in the CRVO and BRVO groups, respectively) [14,34,37].…”

Cataract Surgery Is Not Associated with Decreased Risk of Retinal Vein Occlusion

“… 40 A similar trend of finding associations between DR and CRVO, but not with BRVO, were seen in meta-analyses. 41 , 42 In addition to the differences in the distribution of DR, another possible explanation for the discrepancy between our study results and previously published results is that we relied on DR codes rather than systemic diabetes mellitus codes. Thus, we would have considered only cases of diabetes severe enough to be accompanied by ocular manifestations, unlike previous studies.…”

Characteristics of Hematologic Parameters in Young Patients with Retinal Vein Occlusion

“…In this study, the prevalence of hyperlipidemia, hypertension, and diabetes mellitus in patients with RVO was 53.1%, 31.3%, and 9.4%, respectively. These results are consistent with previous studies, which indicated that RVO in young people is usually accompanied by systemic diseases [ 5 , 20 , 21 ]. Thus, comprehensive screening for systemic and hematologic factors is an important part of the initial workup of young patients with RVO.…”

Role of Advanced Glycation End Products in Assessment of Diabetes Mellitus as a Risk Factor for Retinal Vein Occlusion

“…HTN was the most common risk factor in both groups of RVO, although HTN was significantly more frequent in the BRVO group (in 81.8% in BRVO compared to 58.3% in CRVO group). These findings agreed with data from other authors [14,38,45]. Similar to data from the literature, in this study, hyperlipidemia was noted in approximately 20% of RVO cases (16.7% and 27.3% in the CRVO and BRVO groups, respectively) [14,34,37].…”

Cataract Surgery Is Not Associated with Decreased Risk of Retinal Vein Occlusion

“… 40 A similar trend of finding associations between DR and CRVO, but not with BRVO, were seen in meta-analyses. 41 , 42 In addition to the differences in the distribution of DR, another possible explanation for the discrepancy between our study results and previously published results is that we relied on DR codes rather than systemic diabetes mellitus codes. Thus, we would have considered only cases of diabetes severe enough to be accompanied by ocular manifestations, unlike previous studies.…”

Characteristics of Hematologic Parameters in Young Patients with Retinal Vein Occlusion

“…In this study, the prevalence of hyperlipidemia, hypertension, and diabetes mellitus in patients with RVO was 53.1%, 31.3%, and 9.4%, respectively. These results are consistent with previous studies, which indicated that RVO in young people is usually accompanied by systemic diseases [ 5 , 20 , 21 ]. Thus, comprehensive screening for systemic and hematologic factors is an important part of the initial workup of young patients with RVO.…”

Role of Advanced Glycation End Products in Assessment of Diabetes Mellitus as a Risk Factor for Retinal Vein Occlusion

“…HTN was the most common risk factor in both groups of RVO, although HTN was significantly more frequent in the BRVO group (in 81.8% in BRVO compared to 58.3% in CRVO group). These findings agreed with data from other authors [14,38,45]. Similar to data from the literature, in this study, hyperlipidemia was noted in approximately 20% of RVO cases (16.7% and 27.3% in the CRVO and BRVO groups, respectively) [14,34,37].…”