Retinal Phlebitis with Chorioretinal Emboli

A comparative study of epiretinal membranes associated with Eales' disease: a clinicopathologic evaluation

“…Currently, Eales' disease is in essence a diagnosis of exclusion of the diseases that are known to be associated with retinal vasculitis. [31][32][33][34][35][36][37][38][39][40][41][42][43][44][45] Epiretinal membranes obtained from the patients with Eales' disease could form a good specimen to study the aetiopathogenesis. 7 In its proliferative stages, Eales' disease mimics other vasoproliferative disorders like diabetic retinopathy and vascular occlusions.…”

“…Several immune-mediated diseases including Behcet's disease, sarcoidosis, rhematoid arthritis, Vogt-Koyanagi-Harada, Wegener's granulomatosis, and Crohn's disease causing retinal vasculitis are known to be associated with lymphocytic infiltration of the affected tissues. [32][33][34][35][36][37][38][39][40][41][42][43][44][45] Since we had excluded all the aforementioned conditions, lymphocytic infiltration in the ERMs was least expected. Our observation supports the hypothesis of triggering of immune mechanism by an unknown antigen in patients of Eales' disease resulting in active perivasculitis and resultant cascade of events observed at different stages of the disease process.…”

“…The use of molecular diagnostic techniques could be useful in understanding the aetiopathogenesis of Eales' disease. [48][49][50] We hypothesize that a common protein sequence acts as an antigenic stimulus for an immune cascade that results in perivasculitis characteristic of Eales' disease. Prospective studies are needed in arriving at the common sequence that is responsible for triggering such an immune cascade.…”

Branch Retinal Arterial Occlusion Treated With Intravenous Prostaglandin E1 and Steroids

“…1,2 Visual loss can result from ischemic retina in the posterior pole, which has a whitish color on clinical examination. The immediate restoration of retinal blood flow is probably essential for good visual recovery.…”