Abstract:<div>Retinal degeneration is a leading cause of vision impairment and blindness worldwide and
medical care for advanced disease does not exist. Stem cell-derived retinal organoids (RtOgs)
became an emerging tool for tissue replacement therapy. However, existing RtOg production
methods are highly heterogeneous. Controlled and predictable methodology and tools are needed
to standardize RtOg production and maintenance. In this study, we designed a shear stress-free
micro-millifluidic bioreactor. We used a s… Show more
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