Retinal Nerve Fiber Layer Thickness in Optic Tract Syndrome

Tatsumi, Yasuko; Kanamori, Akira; Kusuhara, Azusa; Nakanishi, Yasutaka; Kusuhara, Sentaro; Nakamura, Makoto

doi:10.1007/s10384-005-0195-y

Cited by 22 publications

(18 citation statements)

References 4 publications

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“…27 Thinning of the RNFL was asymmetric and topographically congruent with lesions of the visual pathway located between the chiasm and the occipital lobe. 26,[28][29][30][31] There also is also evidence supporting the correlation between the pattern of both RNFL loss and macular GC thinning and the type of visual field defect in other optic neuropathies. [32][33][34][35][36] Kanamori et al showed how colour-coded maps could help to visualize the pattern of GC thinning in four cases of optic tract syndrome.…”

Section: Discussionmentioning

confidence: 90%

Visual Outcomes, Visual Fields, and Optical Coherence Tomography in Paediatric Craniopharyngioma

Mediero

Noval

Bravo-Ljubetic

et al. 2015

Neuro-Ophthalmology

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Ten patients with craniopharyngioma treated for the first time when younger than 18 were included. This study reviews the visual outcomes and provides information on visual field (VF) and optical coherence tomography (OCT) examination of craniopharyngioma. The best kappa concordance coefficients between VF and OCT parameters of atrophy were obtained for the ganglion cell (GC) thickness and the mean retinal nerve fibre layer (RNFL) thickness. The agreement between GC colour maps and VF defects was good. Optic nerve compression may be detected by RNFL measurement and GC analysis, and this may be valuable to predict visual recovery and in uncooperative patients to evaluate visual damage.

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Section: Discussionmentioning

confidence: 90%

Visual Outcomes, Visual Fields, and Optical Coherence Tomography in Paediatric Craniopharyngioma

Mediero

Noval

Bravo-Ljubetic

et al. 2015

Neuro-Ophthalmology

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“…Optical coherence tomography (OCT) studies have revealed peripapillary retinal nerve fiber layer (pRNFL) loss in patients with various types of cerebral damage, including damage to the frontal, parietal, temporal, and occipital lobes [1], [2], [5], [6]. However, the ganglion cells on the temporal retina of the fovea primarily send their exons to the superior and inferior sectors of the optic nerve head (ONH), including the temporal sector.…”

Section: Introductionmentioning

confidence: 99%

Macular ganglion cell–inner plexiform layer thinning in patients with visual field defect that respects the vertical meridian

Shin

Choi

Park

2014

Graefes Arch Clin Exp Ophthalmol

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Abstract-Background:To compare the thinning patterns of the ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (pRNFL) as measured using Cirrus high-definition optical coherence tomography (HD-OCT) in patients with visual field (VF) defects that respect the vertical meridian.Methods: Twenty eyes of eleven patients with VF defects that respect the vertical meridian were enrolled retrospectively. The thicknesses of the macular GCIPL and pRNFL were measured using Cirrus HD-OCT. The 5% and 1% thinning area index (TAI) was calculated as the proportion of abnormally thin sectors at the 5% and 1% probability level within the area corresponding to the affected VF. The 5% and 1% TAI were compared between the GCIPL and pRNFL measurements.Results: The color-coded GCIPL deviation map showed a characteristic vertical thinning pattern of the GCIPL, which is also seen in the VF of patients with brain lesions. The 5% and 1% TAI were significantly higher in the GCIPL measurements than in the pRNFL measurements (all P < 0.01).Conclusions: Macular GCIPL analysis clearly visualized a characteristic topographic pattern of retinal ganglion cell (RGC) loss in patients with VF defects that respect the vertical meridian, unlike pRNFL measurements. Macular GCIPL measurements provide more valuable information than pRNFL measurements for detecting the loss of RGCs in patients with retrograde degeneration of the optic nerve fibers.

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“…Nasal and temporal cpRNFL reduction may follow optic tract syndrome, in which visual acuity may be preserved, and TON, which is characterized by severely decreased visual acuity and relative afferent pupillary defect. 7,12 According to our results, cpRNFL and GCC reduction in absence of severe visual loss could reflect a retrograde damage following chiasmic compression with sparing of temporal fibers or optic tract syndrome. Post-traumatic macular discoloration has been related to an outer retinal segment disruption rather than to the presence of an intraretinal edema, because there is no histological evidence for fluid accumulation in acute traumatic maculopathy.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of retinal nerve fiber layer and ganglion cell complex thickness after ocular blunt trauma

Cennamo

Forte

Reibaldi

et al. 2013

Eye

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Purpose To evaluate circumpapillary retinal nerve fiber layer (cpRNFL) and ganglion cell complex (GCC) after ocular blunt trauma. Methods Best-corrected visual acuity (BCVA), cpRNFL and GCC were evaluated by RTVue-100 OCT in all consecutive patients with previous monocular blunt trauma seen between January 2012 and December 2012. Results Twenty-two patients (11 females, 11 males, mean age 43.9±14.2 years) were included in the study. Patients were seen after a mean of 8.42 ± 13.3 (range, 0.08-55.3) years from ocular blunt trauma. BCVA was normal in 11 cases and was less than 0.4 LogMAR in all cases. In 9/22 patients (40.9%), cpRNFL and GCC were reduced, whereas in one case an isolated reduction of GCC with normal cpRNFL was present. In patients with reduction of cpRNFL and GCC, mean BCVA was 0.17 ± 0.17 LogMAR. In 6/9 patients (66.6%) with cpRNFL and GCC reduction, BCVA was r0.1 LogMAR. Conclusion cpRNFL and GCC reduction may be present after ocular blunt trauma and may be associated with preserved visual acuity.

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Retinal Nerve Fiber Layer Thickness in Optic Tract Syndrome

Abstract: OCT can determine the RNFLT reduction corresponding to the characteristic patterns of optic atrophy of OTS.

Cited by 22 publications

References 4 publications

Visual Outcomes, Visual Fields, and Optical Coherence Tomography in Paediatric Craniopharyngioma

Visual Outcomes, Visual Fields, and Optical Coherence Tomography in Paediatric Craniopharyngioma

Macular ganglion cell–inner plexiform layer thinning in patients with visual field defect that respects the vertical meridian

Evaluation of retinal nerve fiber layer and ganglion cell complex thickness after ocular blunt trauma

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