Retinal Nerve Fiber Layer Protrusion Associated with Tilted Optic Discs

Chiang, Jaclyn; Yapp, Michael; Ly, Angelica; Hennessy, Michael; Kalloniatis, Michael; Zangerl, Barbara

doi:10.1097/opx.0000000000001179

Cited by 1 publication

(1 citation statement)

References 28 publications

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“…They suggested that PHOMS occurs because optic disc tilting leads to distention of the axons that herniate into the peripapillary retina. Similarly, Chiang et al (72) demonstrated that congenital disc tilt (disc torsion greater than 45 • and the tilting occurred inferonasally) correlated with a dome-shaped hyperreflective RNFL bulge that protrudes into the retina at the optic disc margin, which could be due to the convergence of a normal number of axons into a small sclera foramen, followed by loss of cupping. The margins become indistinctive due to the compression and bending of the converged axons at an oblique angle.…”

Section: Disc Rim and Peripapillary Areamentioning

confidence: 92%

Myopic tilted disc: Mechanism, clinical significance, and public health implication

2023

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Myopic tilted disc is a common structural change of myopic eyes. With advancing ocular imaging technology, the associated structural changes of the eye, particularly the optic nerve head, have been extensively studied. These structural changes may increase patients’ susceptibility to axonal damage and the risk of developing serious optic neuropathies including glaucoma. They also lead to diagnostic difficulties of disease suspects and treatment dilemmas of patients, which implicate clinical practice and subsequently the health care system. In the context of the mounting prevalence of myopia worldwide and its implications to irreversible visual impairment and blindness, it is essential to gain a thorough understanding of the structural changes of myopia. Myopic tilted disc has been extensively investigated by different study groups. However, generalizing the knowledge could be difficult because of the variable definitions of myopic tilted disc utilized in these studies and the complexities of the changes. The current review aimed to clarify the concepts and discuss various aspects of myopic tilted disc, including the definitions, association with other myopia-related changes, mechanism of tilted disc development, structural and functional changes, and clinical implications.

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Section: Disc Rim and Peripapillary Areamentioning

confidence: 92%