Retinal Ischemia in Diabetic Retinopathy

Foveal Avascular Zone Enlargement Correlates with Visual Acuity Decline in Patients with Diabetic Retinopathy

“…Even amongst study eyes graded as quiescent PDR, which would be expected to experience the greatest degree of visual impairment, mean BCVA letter score was 79.8 (Snellen equivalent 20/32) with only 8 of 59 eyes (13.6%) having a BCVA letter score ≤ 70. These findings are consistent with previous studies and suggest that despite profound retinal ischemia, patients may still experience normal or near-normal visual acuity 41 , 42 . Our findings may be attributed in part to the exclusion of DME and other ocular pathologies that confound the effect of the structural or functional FAZ in our study.…”

Foveal Avascular Zone Enlargement Correlates with Visual Acuity Decline in Patients with Diabetic Retinopathy

“…Even amongst study eyes graded as quiescent PDR, which would be expected to experience the greatest degree of visual impairment, mean BCVA letter score was 79.8 (Snellen equivalent 20/32) with only 8 of 59 eyes (13.6%) having a BCVA letter score ≤ 70. These findings are consistent with previous studies and suggest that despite profound retinal ischemia, patients may still experience normal or near-normal visual acuity 41 , 42 . Our findings may be attributed in part to the exclusion of DME and other ocular pathologies that confound the effect of the structural or functional FAZ in our study.…”

The relationship between perifoveal capillary ring alterations and visual acuity in diabetic retinopathy

“…The similar relationship was also found in the eyes with PDR Our results suggest that ischemic maculopathy may be compatible with good visual acuity if not accompanied by edema. Occurrence of macular edema caused by leakage from residual macular capillaries leads to a greater decrease in visual acuity which is in agreement with the findings of other studies 14,19 . As mentioned earlier, the fluorescein leakage does not always correlate with retinal thickness.…”

Localised scotomata and types of vascular occlusion in diabetic retinopathy

“…Apart from the abruptly occluded vessel, the retinal morphology corresponding to the scotomata appeared normal on fluorescein angiograms in these cases, except for slight hypofluorescence of the retinal background. This hypofluorescence should probably be distinguished from the morphological pattern seen as retinal non-perfusion, Bresnick et al (1976) comfirming the finding of a prior study where visual loss was found in relation to closure of larger retinal arterioles, mainly in advanced and rapidly progressing retinopathy (Bresnick et al 1975(Bresnick et al , 1976.…”

Foveal Avascular Zone Enlargement Correlates with Visual Acuity Decline in Patients with Diabetic Retinopathy

“…Even amongst study eyes graded as quiescent PDR, which would be expected to experience the greatest degree of visual impairment, mean BCVA letter score was 79.8 (Snellen equivalent 20/32) with only 8 of 59 eyes (13.6%) having a BCVA letter score ≤ 70. These findings are consistent with previous studies and suggest that despite profound retinal ischemia, patients may still experience normal or near-normal visual acuity 41 , 42 . Our findings may be attributed in part to the exclusion of DME and other ocular pathologies that confound the effect of the structural or functional FAZ in our study.…”

The relationship between perifoveal capillary ring alterations and visual acuity in diabetic retinopathy

“…The similar relationship was also found in the eyes with PDR Our results suggest that ischemic maculopathy may be compatible with good visual acuity if not accompanied by edema. Occurrence of macular edema caused by leakage from residual macular capillaries leads to a greater decrease in visual acuity which is in agreement with the findings of other studies 14,19 . As mentioned earlier, the fluorescein leakage does not always correlate with retinal thickness.…”

Localised scotomata and types of vascular occlusion in diabetic retinopathy

“…Apart from the abruptly occluded vessel, the retinal morphology corresponding to the scotomata appeared normal on fluorescein angiograms in these cases, except for slight hypofluorescence of the retinal background. This hypofluorescence should probably be distinguished from the morphological pattern seen as retinal non-perfusion, Bresnick et al (1976) comfirming the finding of a prior study where visual loss was found in relation to closure of larger retinal arterioles, mainly in advanced and rapidly progressing retinopathy (Bresnick et al 1975(Bresnick et al , 1976.…”

Foveal Avascular Zone Enlargement Correlates with Visual Acuity Decline in Patients with Diabetic Retinopathy

“…Even amongst study eyes graded as quiescent PDR, which would be expected to experience the greatest degree of visual impairment, mean BCVA letter score was 79.8 (Snellen equivalent 20/32) with only 8 of 59 eyes (13.6%) having a BCVA letter score ≤ 70. These findings are consistent with previous studies and suggest that despite profound retinal ischemia, patients may still experience normal or near-normal visual acuity 41 , 42 . Our findings may be attributed in part to the exclusion of DME and other ocular pathologies that confound the effect of the structural or functional FAZ in our study.…”

The relationship between perifoveal capillary ring alterations and visual acuity in diabetic retinopathy

“…The similar relationship was also found in the eyes with PDR Our results suggest that ischemic maculopathy may be compatible with good visual acuity if not accompanied by edema. Occurrence of macular edema caused by leakage from residual macular capillaries leads to a greater decrease in visual acuity which is in agreement with the findings of other studies 14,19 . As mentioned earlier, the fluorescein leakage does not always correlate with retinal thickness.…”

Localised scotomata and types of vascular occlusion in diabetic retinopathy

“…Apart from the abruptly occluded vessel, the retinal morphology corresponding to the scotomata appeared normal on fluorescein angiograms in these cases, except for slight hypofluorescence of the retinal background. This hypofluorescence should probably be distinguished from the morphological pattern seen as retinal non-perfusion, Bresnick et al (1976) comfirming the finding of a prior study where visual loss was found in relation to closure of larger retinal arterioles, mainly in advanced and rapidly progressing retinopathy (Bresnick et al 1975(Bresnick et al , 1976.…”