1951
DOI: 10.1148/57.5.653
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Reticulo-Endotheliosis of Children: Treatment with Roentgen Rays

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Cited by 30 publications
(6 citation statements)
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“…Radiation therapy, which is beneficial with the osseous lesions of HSCD (as it actually was in our patient) was reported as effective also in some cases of cerebral HX [4,25]. Metho trexate treatment was successful in Newton and Anderson's [21] case, while cortisone and y-globulin therapy were useful in the cases of Letterer-Siwe's disease reported by Duperral et al [9] and by LeCat and Crupper [15].…”
Section: Discussionsupporting
confidence: 61%
“…Radiation therapy, which is beneficial with the osseous lesions of HSCD (as it actually was in our patient) was reported as effective also in some cases of cerebral HX [4,25]. Metho trexate treatment was successful in Newton and Anderson's [21] case, while cortisone and y-globulin therapy were useful in the cases of Letterer-Siwe's disease reported by Duperral et al [9] and by LeCat and Crupper [15].…”
Section: Discussionsupporting
confidence: 61%
“…It is used as a single treatment option for either bony lesions or other organ involvement but also in a multimodal approach in combination with chemotherapy (CTX), surgery or steroids [6,13-16]. The mechanism of actions induced by ionizing radiation target cells remains unclear [7,17-21].…”
Section: Introductionmentioning
confidence: 99%
“…For several decades, radiotherapy (RT) has been reported to be effective even at very low doses for osseous manifestations of LCH, either as a single treatment, or in combination with other modalities like chemotherapy (CT), surgery or steroids [10,22,27]. The target cells and mechanisms of ionizing radiation actions remain unclear [26,33,36,37,45]; a high sensitivity of Langerhans cells to RT and an RT-induced suppression of inflammatory processes have been discussed [21].…”
Section: Introductionmentioning
confidence: 99%