Reticulate porokeratosis-successful treatment with CO2-laser vaporization

Merkle, Tanja; Hohenleutner, Ulrích; Braun‐Falco, Otto; Thaler, Marlene

doi:10.1111/j.1365-2230.1992.tb00200.x

Cited by 18 publications

(5 citation statements)

References 13 publications

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“…Treatment options for porokeratosis of Mibelli are limited and often suboptimal. They include topical S-fluorouracil (33), topical and intralesional corticosteroids (34), cryosurgery (7), electrodesiccation (7), curettage (34), excision (34,35), dermabrasion (34), and CO-, laser vaporization (35)(36)(37). 5-F!uorouracil cream and laser vaporization with curettage failed in our patient, and excision was necessary.…”

Section: Discussionmentioning

confidence: 91%

Porokeratosis of Mibelli: Rapid Recurrence of a Large Lesion After Carbon Dioxide Laser Treatment

McCullough

Lesher

1994

Pediatric Dermatology

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Porokeratosis of Mibelli was diagnosed in a 9-year-old Afro-American girl. The lesion was rather large (4.1 x 2.0 cm) and had developed rapidly over the course of six months. Considering the potential for malignant transformation without neglecting the importance of cosmesis, carbon dioxide laser vaporization with curettage was chosen to ablate the lesion. Within two months the entire treated area revealed recurrent porokeratosis. Due to the aggressive nature of this lesion, complete excision was performed.

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Section: Discussionmentioning

confidence: 91%

Porokeratosis of Mibelli: Rapid Recurrence of a Large Lesion After Carbon Dioxide Laser Treatment

McCullough

Lesher

1994

Pediatric Dermatology

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“…Surgical treatments include cryotherapy, shave and curettage, electrodesiccation. excision, carbon dioxide laser, and dermabrasion (2,22,23,(27)(28)(29). Superficial procedures tend to result in recurrences.…”

Section: Discussionmentioning

confidence: 99%

Linear Porokeratosis Presenting as Erosions in the Newborn Period

Fisher

LeBoit²,

Frieden

1995

Pediatric Dermatology

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The classic appearance of porokeratosis is characterized by a hyperkeratotic annular rim that expands peripherally, leaving an atrophic center. Linear porokeratosis is a variant with collections of such lesions arranged in a linear fashion, usually corresponding to a dermatome or Blaschko's lines. Ulcerations have rarely been reported in patients with porokeratosis. We report an unusual case of linear porokeratosis at birth, with erosions and ulcerations of the face and lower extremity, that eluded diagnosis for nearly a year. Porokeratosis should be considered in the differential diagnosis of erosions in the newborn period.

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“…Complete clearance with no relapse within 1-12 years was noted in three VP cases treated using a CO 2 laser [467,514], whereas in nine, the lesions recurred after up to 13 years [6,191,290,465,467,474,475,507]. An excellent therapeutic outcome in six patients with localised VP lesions was achieved using CO 2 lasers or surgery (no precise data) [469].…”

Section: Treatmentmentioning

confidence: 99%

Porokeratoses—A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants

Pietkiewicz,

Korecka,

Salwowska

et al. 2023

Metabolites

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Porokeratosis is a heterogeneous group of keratinising disorders characterised by the presence of particular microscopic structural changes, namely the presence of the cornoid lamella. This structure develops as a consequence of a defective isoprenoid pathway, critical for cholesterol synthesis. Commonly recognised variants include disseminated superficial actinic porokeratosis, disseminated superficial porokeratosis, porokeratosis of Mibelli, palmoplantar porokeratosis (including porokeratosis palmaris et plantaris disseminata and punctate porokeratosis), linear porokeratosis, verrucous porokeratosis (also known as genitogluteal porokeratosis), follicular porokeratosis and porokeratoma. Apart from the clinical presentation and epidemiology of each variant listed, this review aims at providing up-to-date information on the precise genetic background, introduces imaging methods facilitating the diagnosis (conventional and ultraviolet-induced fluorescence dermatoscopy, reflectance confocal microscopy and pathology), discusses their oncogenic potential and reviews the literature data on the efficacy of the treatment used, including the drugs directly targeting the isoprenoid–mevalonate pathway.

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Reticulate porokeratosis-successful treatment with CO2-laser vaporization

Abstract: A 35-year-old male patient affected with extensive, itching skin lesions of reticulate porokeratosis is reported. He was successfully treated by CO2-laser vaporization.

Cited by 18 publications

References 13 publications

Porokeratosis of Mibelli: Rapid Recurrence of a Large Lesion After Carbon Dioxide Laser Treatment

Porokeratosis of Mibelli: Rapid Recurrence of a Large Lesion After Carbon Dioxide Laser Treatment

Linear Porokeratosis Presenting as Erosions in the Newborn Period

Porokeratoses—A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants

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