Reticular Dystrophy of the Retinal Pigment Epithelium

Abstract

A laser flare-cell meter was used to examine blood-aqueous barrier function in a 57-year-old male patient who had typical reticular dystrophy of the retinal pigment epithelium with a bilateral hyperpigmented reticular pattern at the posterior pole in both eyes. Fluorescein angiography showed hypofluorescent reticular net resembling a fishing net with knots associated with a central diffuse hyperfluorescence. Dark adaptation test revealed that the final rod threshold was elevated. Laser photometry showed an increase in the aqueous flare intensity in both eyes, as compared to the results in normal subjects. Quantitative measurement of the aqueous flare intensity by a laser flare-cell meter might indicate abnormalities in the blood-aqueous barrier in patients with reticular dystrophy of the retinal pigment epithelium.

Electrophysiological Evaluation of Macular Dystrophies

“…Sjogren’s reticular pattern dystrophy (RPD, OMIM 267800) is characterized by the presence of yellow deposits at the level of the RPE with a reticular pattern [ 115 ]. The pattern can be highlighted as a hyperfluorescent reticular net on FA [ 116 ]. The patient with RPD can present with normal or reduced vision.…”

“…The patient with RPD can present with normal or reduced vision. In electrophysiological testing, RPD patients have been reported to have normal scotopic and photopic ffERG [ 116 , 117 , 118 ]. RPD patients can have normal to mildly reduced EOG, with the LP:DT ratio ranging from 1.52–2.07 [ 116 , 117 ].…”