Resveratrol increase the proportion of oxidative muscle fiber through the AdipoR1-AMPK-PGC-1α pathway in pigs

The Effect of Dietary Supplementation with Resveratrol on Growth Performance, Carcass and Meat Quality, Blood Lipid Levels and Ruminal Microbiota in Fattening Goats

“…In this study, we observed that different supplemental levels of RES had different effects on the growth performance and carcass characteristics of goats. Treatment with 300 mg/kg RES for 120 d had no significant effect on food intake, body weight or carcass characteristics, which is consistent with some previous studies in mice and pigs [ 5 , 6 , 21 ]. Dietary RES supplementation has previously been found to have no significant effects on carcass characteristics including carcass weight, dressing percentage and LD muscle area in finishing pigs [ 6 , 21 ].…”

“…Our results demonstrated that RES could greatly improve blood lipid profiles in fattening goats. The blood physiological indexes showed that RES had no obvious effect on the health of goats, which was consistent with the study reported by Huang et al (2020) [ 5 ].…”

“…Recently, more and more scholars have performed numerous studies on the effects of RES supplementation in livestock and poultry production. In poultry, dietary RES supplementation has been shown to improve the quality of pork by changing the muscle fiber characteristics and antioxidant capacity [ 5 , 6 ]. Moreover, RES has been shown to act as an antioxidant to reduce the degradation in meat quality observed in broilers subjected to transport and heat stresses [ 7 , 8 ].…”

Resveratrol Inhibits Proliferation and Differentiation of Porcine Preadipocytes by a Novel LincRNA-ROFM/miR-133b/AdipoQ Pathway

“…RES is a plant polyphenol that exists in grapes, peanuts, mulberries, pomegranates, and berries, and has been considered a potential functional food/feed additive [ 24 ]. RES has been widely reported to involve in a wide range of biological activities [ 25 ], including anti-inflammatory [ 26 ], anticancer [ 27 ], antioxidant [ 28 , 29 ], preventing obesity [ 30 ], and treating diabetes [ 31 ]. In animal husbandry, RES can increase the proportion of oxidative muscle fiber by the AdipoR1-AMPK-PGC-1α pathway to improve pork quality [ 25 ] and improve the growth performance, meat percentage, and meat quality of fattening goat [ 32 ].…”

“…RES has been widely reported to involve in a wide range of biological activities [ 25 ], including anti-inflammatory [ 26 ], anticancer [ 27 ], antioxidant [ 28 , 29 ], preventing obesity [ 30 ], and treating diabetes [ 31 ]. In animal husbandry, RES can increase the proportion of oxidative muscle fiber by the AdipoR1-AMPK-PGC-1α pathway to improve pork quality [ 25 ] and improve the growth performance, meat percentage, and meat quality of fattening goat [ 32 ]. Moreover, RES was also found to affect lipid metabolism, and regulate adipocyte proliferation, differentiation, and apoptosis [ 3 ] by PPARγ [ 33 ], PKA/AMPK/PPARα [ 34 ], and Mtor [ 35 ] pathway.…”