Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) Use in Animal Trauma Models

Kinslow, Kyle; Shepherd, Aaron; Sutherland, Mason; McKenney, Mark; Elkbuli, Adel

doi:10.1016/j.jss.2021.06.052

Cited by 5 publications

(9 citation statements)

References 34 publications

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“…While the ER-REBOA has been shown to be useful in hemorrhage control, it has a high rate of ischemia-reperfusion-related complications, including limb ischemia, spinal cord ischemia, visceral organ dysfunction, and AKI. [13][14][15] The results from this case series suggest that patients with pREBOA placement have a significantly lower risk of developing an AKI compared to ER-REBOA, with no difference in mortality, rhabdomyolysis, and amputations.…”

Section: Discussionmentioning

confidence: 71%

“…14 Serum lactate, acidosis, inflammatory cytokines, and cardiac injury were found to be significantly higher in the total occlusion group compared to the partial occlusion group. 14,15 Overall, animal models indicate that partial aortic occlusion provides similar modynamic support without the ischemic complications of complete aortic occlusion. [9][10][11]14,15 Outside of animal models, research comparing the use of ER-REBOA and pREBOA in clinical settings is somewhat limited.…”

Section: Discussionmentioning

confidence: 87%

“…When comparing total vs partial aortic occlusion in animal models, there was significant morbidity and mortality benefit with partial occlusion. [9][10][11]14,16 Partial REBOA techniques were found to attain similar proximal mean arterial blood pressure when compared to the Complete REBOA (cREBOA). Additionally, partial REBOA was found to have a lesser distal ischemic burden, demonstrated through significantly lower levels of lab parameters for end organ damage (lactate and liver function tests).…”

Section: Discussionmentioning

confidence: 91%

“…14,15 Overall, animal models indicate that partial aortic occlusion provides similar modynamic support without the ischemic complications of complete aortic occlusion. [9][10][11]14,15 Outside of animal models, research comparing the use of ER-REBOA and pREBOA in clinical settings is somewhat limited. Some recent studies, however, have found partial aortic occlusion to be superior to complete aortic occlusion in terms of ischemic complications.…”

Section: Discussionmentioning

confidence: 98%

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Acute Kidney Injury in Hypotensive Trauma Patients Following Resuscitative Endovascular Balloon Occlusion of the Aorta Placement

Hunt

Gold

Hunt

et al. 2023

The American Surgeon™

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Background ER-Resuscitative Endovascular Balloon Occlusion of the Aorta (ER-REBOA) is an adjunct tool to achieve hemostasis in trauma patients with non-compressible torso hemorrhage. The development of the partial REBOA (pREBOA) allows for distal perfusion of organs while maintaining occlusion of the aorta. The primary aim of this study was to compare rates of acute kidney injury (AKI) in trauma patients who had placement of either a pREBOA or ER-REBOA. Methods A retrospective chart review of adult trauma patients who underwent REBOA placement between September 2017 and February 2022 was performed. Baseline demographics, information on REBOA placement, and post-procedure complications including AKI, amputations, and mortality were recorded. Chi-squared and T-test analyses were performed with P < .05 considered to be significant. Results A total of 68 patients met study inclusion criteria with 53 patients (77.9%) having an ER-REBOA. 6.7% of patients treated with pREBOA had a resulting AKI, while 40% of patients treated with ER-REBOA had a resulting AKI, and this difference was significant ( P < .05). The rates of rhabdomyolysis, amputations, and mortality were not significantly different between the two groups. Conclusion The results from this case series suggest that patients treated with pREBOA have a significantly lower incidence of developing an AKI compared to ER-REBOA. There were no significant differences in rates of mortality, and amputations. Future prospective studies are needed to further characterize the indications and optimal use for pREBOA.

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Section: Discussionmentioning

confidence: 71%

Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 98%

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Acute Kidney Injury in Hypotensive Trauma Patients Following Resuscitative Endovascular Balloon Occlusion of the Aorta Placement

Hunt

Gold

Hunt

et al. 2023

The American Surgeon™

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“…In contrast, complete occlusion of the aorta could lead to proximal hypertension and increase the hemorrhage at the proximal side of the balloon [6]. Recently, studies concerning the effectiveness of partial REBOA have been increasingly published [7][8][9][10][11][12][13][14][15][16][17].…”

Section: Partial Reboamentioning

confidence: 99%

Partial Resuscitative Endovascular Balloon Occlusion of the Aorta and Intermittent Resuscitative Endovascular Balloon Occlusion of the Aorta

Kurihara

Maruhashi

Matsumura³

2022

JEVTM

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Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a resuscitation procedure for severe hemorrhagic shock. While complete occlusion of the aorta could be effective for the control of blood flow, there is always a concern for ischemia-reperfusion injury of the distal organs from the balloon catheter. REBOA can control the degree of occlusion by changing the injection volume of the balloon catheter. Partial REBOA and intermittent REBOA are some of the strategies of REBOA, with which less ischemia-perfusion injury is done, rather than complete occlusion of the aorta, although evidence on partial REBOA and intermittent REBOA is still limited.

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Partial Resuscitative Endovascular Balloon Occlusion of the Aorta Limits Ischemia-Reperfusion Injury After Simulated Aeromedical Evacuation

Singer

Wallen

Youngs

et al. 2023

Journal of Surgical Research

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Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) Use in Animal Trauma Models

Cited by 5 publications

References 34 publications

Acute Kidney Injury in Hypotensive Trauma Patients Following Resuscitative Endovascular Balloon Occlusion of the Aorta Placement

Acute Kidney Injury in Hypotensive Trauma Patients Following Resuscitative Endovascular Balloon Occlusion of the Aorta Placement

Partial Resuscitative Endovascular Balloon Occlusion of the Aorta and Intermittent Resuscitative Endovascular Balloon Occlusion of the Aorta

Partial Resuscitative Endovascular Balloon Occlusion of the Aorta Limits Ischemia-Reperfusion Injury After Simulated Aeromedical Evacuation

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