Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures

Dhanani, Sonny; Hornby, Laura; Beinum, Amanda van; Scales, Nathan; Hogue, Melanie L; Baker, Andrew J.; Beed, Stephen; Boyd, J. Gordon; Chandler, Jennifer A.; Chassé, Michaël; D’Aragon, Frédérick; Dezfulian, Cameron; Doig, Christopher J.; Duska, F; Friedrich, Jan O.; Gardiner, Dale; Gofton, Teneille; Harvey, Dan; Herry, Christophe L.; Isac, George; Kramer, Andreas H.; Kutsogiannis, Demetrios J; Maslove, David; Meade, Maureen O.; Mehta, Sangeeta; Munshi, Laveena; Norton, Loretta; Pagliarello, Giuseppe; Ramsay, Tim; Rusínová, Kateřina; Scales, Damon C.; Schmidt, Matouš; Seely, Andrew J. E.; Shahin, Jason; Slessarev, Marat; So, Derek; Talbot, Heather; Mook, Walther N. K. A. van; Waldauf, Petr; Weiss, Matthew J.; Wind, Jentina; Shemie, Sam D.

doi:10.1056/nejmoa2022713

Cited by 75 publications

(49 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…From an ethical viewpoint, the definition of death in DCD settings is generally accepted as the ‘permanent’ rather than the ‘irreversible’ cessation of circulation [42–47]. ‘Permanent’ means that no efforts are made to restart circulation and autoresuscitation is no longer possible.…”

Section: Ethical Considerations When Implementing Nrpmentioning

confidence: 99%

“…‘Permanent’ means that no efforts are made to restart circulation and autoresuscitation is no longer possible. This point is commonly accepted to be achieved after 5 minutes of continuous apnoea, circulatory loss and unresponsiveness, but in some countries, legislation requires a longer observational period [45].…”

Section: Ethical Considerations When Implementing Nrpmentioning

confidence: 99%

See 1 more Smart Citation

Consensus statement on normothermic regional perfusion in donation after circulatory death: Report from the European Society for Organ Transplantation’s Transplant Learning Journey

et al. 2021

View full text Add to dashboard Cite

Summary Normothermic regional perfusion (NRP) in donation after circulatory death (DCD) is a safe alternative to in situ cooling and rapid procurement. An increasing number of countries and centres are performing NRP, a technically and logistically challenging procedure. This consensus document provides evidence‐based recommendations on the use of NRP in uncontrolled and controlled DCDs. It also offers minimal ethical, logistical and technical requirements that form the foundation of a safe and effective NRP programme. The present article is based on evidence and opinions formulated by a panel of European experts of Workstream 04 of the Transplantation Learning Journey project, which is part of the European Society for Organ Transplantation.

show abstract

Section: Ethical Considerations When Implementing Nrpmentioning

confidence: 99%

Section: Ethical Considerations When Implementing Nrpmentioning

confidence: 99%

Consensus statement on normothermic regional perfusion in donation after circulatory death: Report from the European Society for Organ Transplantation’s Transplant Learning Journey

et al. 2021

View full text Add to dashboard Cite

show abstract

“…All these events occurred within 4 minutes 20 seconds after the period of pulselessness. 37 COVID-19 continues to remain and prevail almost in all the articles in this issue of SCVA. Now that we have the majority patients recovering from COVID-19, several of them continue to have one or the other symptom like persistent dyspnea, persistent fatigue, malaise, cognitive clouding well after 4-week when they are polymerase chain reaction test negative.…”

mentioning

confidence: 95%

The Year 2020 in Review: Coronavirus Disease 2019 Cloud and Its Impact Excelling the Clinical Practice

Pal

Weitzel

Kertai

2021

Semin Cardiothorac Vasc Anesth

View full text Add to dashboard Cite

show abstract

“…Advanced life sustaining technologies such as breathing machines and drugs used to artificially maintain blood pressure blur the lines between life and death, as well as the limits of ethical responsibility with assigning human death. Sophisticated physiological monitoring has demonstrated the persistence of certain electrical signals in the heart long after the last breath has been drawn (Dhanani et al 2014(Dhanani et al , 2021. And the success of deceased organ donation itself assures us that declared death of the body does not necessarily signify the end of organ activity.…”

Section: List Of Illustrationsmentioning

confidence: 99%

“…Throughout my fieldwork and over the course of this study I continued to be involved in a research project seeking to understand the physiology of death and dying following the removal of life sustaining therapies in the intensive care unit (Dhanani et al 2021). As part of my involvement in this study, I took part in many research meetings as well as attended and presented at larger conferences on critical care medicine and organ donation.…”

Section: Participant Observation and Ethnographer As Apparatusmentioning

confidence: 99%

Reimagining Death: A Posthuman Analysis of Life Support and the Concept of Death in the Intensive Care Unit

Beinum¹

Self Cite

View full text Add to dashboard Cite

Often assumed to be simply the opposite or absence of life, death is in truth a distinctively uncertain category which troubles assumptions about what it means to be alive, and what it means to be human. In this project, I explore what happens to understandings of bodily endings when the "normal human" is de-centered from the concept of death. I take a post-Enlightenment, post-humanist approach in the mode espoused by Rosi Braidotti (2006, 2019) which seeks to move beyond the elite and exclusive category of "human," as well as to get outside of anthropocentric patterns of thought. This project focuses on shifting definitions and meanings of death in the midst of advanced life-sustaining technologies and against a backdrop of cultural fascination with immortality as represented by the modern intensive care unit. Employing ethnographic methods and concepts from feminist new materialism, and founded on an in-depth understanding of posthuman theory, this work contributes novel analyses of how death happens in technological spaces, and how our understandings of it could be approached differently. I contrast cases of patients sustained on life-support technologies seemingly beyond their desired limits with those of individuals declared to be dead against their beliefs to explore ontological, epistemological, and practical elements presently maintaining the appearance of universal definitions of death. A final analysis of media cases of people who continue to produce life through pregnancy despite being categorized as dead helps to reconfigure assumptions about life, death, and life sustaining technologies into a new understanding of how bodily endings, alongside perceptions of liveliness, are always a particular product of ongoing and unfolding social and technical iii | relations. Ultimately, I suggest that life sustaining technologies and their capacity to promote impressions of vitality allow us to better appreciate how death is already always a part of life, a perhaps unwanted "other" that we might learn to tolerate and accept, a personal ethical threshold of existence with the potential to transport us into different futures. This work expands the application of posthuman theory into the domain of clinical death and demonstrates the added value of posthuman analyses in medical spaces. iv | ACKNOWLEDGEMENTS This dissertation was made possible through the intellectual contributions, commitment of time and energy, and emotional care of many, many people. I am also grateful to organizations such as the Canadian Social Science and Humanities Research Council, the Ontario Graduate Scholarship, Carleton University, and the Department of Sociology and Anthropology for making this work and this degree possible through grants and scholarship funding.A huge thank you is owed to my supportive and engaged committee, who have truly helped to guide the direction and improve the focus of this project. To my supervisor, Carlos Novas, thank you for inspiring me to pursue inquiry in the field of STS and posthumanism, and for our ma...

show abstract

Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures

Cited by 75 publications

References 20 publications

Consensus statement on normothermic regional perfusion in donation after circulatory death: Report from the European Society for Organ Transplantation’s Transplant Learning Journey

Consensus statement on normothermic regional perfusion in donation after circulatory death: Report from the European Society for Organ Transplantation’s Transplant Learning Journey

The Year 2020 in Review: Coronavirus Disease 2019 Cloud and Its Impact Excelling the Clinical Practice

Reimagining Death: A Posthuman Analysis of Life Support and the Concept of Death in the Intensive Care Unit

Contact Info

Product

Resources

About